沙利度胺治疗麻风病——94例研究。
Thalidomide in leprosy--study of 94 cases.
作者信息
Parikh D A, Ganapati R, Revankar C R
出版信息
Indian J Lepr. 1986 Oct-Dec;58(4):560-6.
Thalidomide has a beneficial effect on type II Lepra reaction especially chronic and recurrent reaction. It helps to minimise steroid dependency. Thalidomide was given to 94 cases of type II lepra reaction, who had not responded to steroids or had repeated reactions. This clinical data was analysed regarding clinical improvement, relapse of reaction, side effects of the drug, etc. The analysis showed that all the patients improved remarkably and steroids could be withdrawn. If the competence of staff using this drug is enhanced, morbidity due to leprosy can considerably be reduced.
沙利度胺对Ⅱ型麻风反应，尤其是慢性和复发性反应有有益作用。它有助于尽量减少对类固醇的依赖。对94例Ⅱ型麻风反应患者给予沙利度胺，这些患者对类固醇无反应或有反复反应。对该临床数据进行了关于临床改善、反应复发、药物副作用等方面的分析。分析表明，所有患者均有显著改善，类固醇可以停用。如果使用这种药物的工作人员的能力得到提高，麻风病的发病率可大幅降低。
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