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精神病发病前和临床早期个体的自我反思能力与临床症状之间的关系。

Relationships between self-reflectiveness and clinical symptoms in individuals during pre-morbid and early clinical stages of psychosis.

作者信息

Xu Lihua, Cui Huiru, Wei Yanyan, Qian Zhenying, Tang Xiaochen, Hu Yegang, Wang Yingchan, Hu Hao, Guo Qian, Tang Yingying, Zhang Tianhong, Wang Jijun

机构信息

Shanghai Intelligent Psychological Evaluation and Intervention Engineering Technology Research Center, Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Gen Psychiatr. 2022 May 31;35(3):e100696. doi: 10.1136/gpsych-2021-100696. eCollection 2022.

DOI:10.1136/gpsych-2021-100696
PMID:35721834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9161056/
Abstract

BACKGROUND

Self-reflectiveness, one dimension of cognitive insight, plays a protective role in an individual's mental state. Both high and low levels of self-reflectiveness have been reported in patients with schizophrenia and individuals at clinical high risk for the illness.

AIMS

This study aimed to explore the relationship patterns between self-reflectiveness and clinical symptoms in individuals during the pre-morbid and early clinical stages of psychosis.

METHODS

A total of 181 subjects, including individuals with attenuated positive symptoms (APS, n=122) and patients with first-episode psychosis (FEP, n=59), completed the Beck Cognitive Insight Scale and were evaluated using the Schedule of Assessment of Insight and Positive and Negative Syndrome Scale. All subjects were classified into three groups according to their level of self-reflectiveness: low level (LSR, n=59), medium level (MSR, n=67) and high level (HSR, n=55). Both linear and non-linear relationships between self-reflectiveness and clinical symptoms were explored.

RESULTS

More individuals with APS were classified into the MSR group, while more patients with FEP were classified into the LSR group. The LSR group demonstrated less awareness of illness than the MSR and HSR groups, more stereotyped thinking and poorer impulse control but less anxiety than the MSR group, and lower levels of blunted affect and guilt feelings than the HSR group. The MSR group demonstrated lower stereotyped thinking than the HSR group. Compared to the LSR group, the MSR group had increased self-reflectiveness, improved awareness of illness, decreased stereotyped thinking, and better impulse control, but increased feelings of guilt. The HSR group showed increased stereotyped thinking when compared to the MSR group, but the other variables did not change significantly between these two groups. Overall, self-reflectiveness demonstrated an approximately inverse S-shaped relationship with the awareness of illness, a U-shaped relationship with stereotyped thinking and poor impulse control, and an almost linear relationship with anxiety and guilt feelings.

CONCLUSIONS

Self-reflectiveness demonstrates complex relationships with clinical symptoms and fails to exert significant positive effects when reaching a certain high level.

摘要

背景

自我反思是认知洞察力的一个维度,对个体的心理状态起保护作用。精神分裂症患者及临床高危个体中均有自我反思水平高和低的报道。

目的

本研究旨在探讨精神病前和临床早期个体的自我反思与临床症状之间的关系模式。

方法

共有181名受试者,包括症状轻微的阳性症状个体(APS,n = 122)和首发精神病患者(FEP,n = 59),完成了贝克认知洞察量表,并使用洞察评估量表以及阳性和阴性症状量表进行评估。所有受试者根据其自我反思水平分为三组:低水平(LSR,n = 59)、中等水平(MSR,n = 67)和高水平(HSR,n = 55)。探讨了自我反思与临床症状之间的线性和非线性关系。

结果

更多的APS个体被归类到MSR组,而更多的FEP患者被归类到LSR组。LSR组比MSR组和HSR组表现出更低的疾病自知力,更多的刻板思维和更差的冲动控制,但比MSR组焦虑更少,比HSR组情感迟钝和内疚感水平更低。MSR组比HSR组表现出更低的刻板思维。与LSR组相比,MSR组自我反思增加,疾病自知力提高,刻板思维减少,冲动控制更好,但内疚感增加。与MSR组相比,HSR组表现出更多的刻板思维,但两组之间的其他变量没有显著变化。总体而言,自我反思与疾病自知力呈近似倒S形关系,与刻板思维和冲动控制差呈U形关系,与焦虑和内疚感呈近似线性关系。

结论

自我反思与临床症状表现出复杂的关系,在达到一定高水平时未能发挥显著的积极作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/c1cb1c2fd36a/gpsych-2021-100696f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/65e632f04e44/gpsych-2021-100696f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/7a8ae2b7a3ee/gpsych-2021-100696f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/c1cb1c2fd36a/gpsych-2021-100696f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/65e632f04e44/gpsych-2021-100696f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/7a8ae2b7a3ee/gpsych-2021-100696f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de6/9161056/c1cb1c2fd36a/gpsych-2021-100696f04.jpg

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本文引用的文献

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2
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JAMA Psychiatry. 2021 Jun 16;78(8):859-67. doi: 10.1001/jamapsychiatry.2021.1290.
3
Large-scale evaluation of the Positive and Negative Syndrome Scale (PANSS) symptom architecture in schizophrenia.
基于对临床高风险精神病个体评估的预防进展与未来方向:来自SHARP研究的见解
Schizophr Bull. 2025 Mar 14;51(2):343-351. doi: 10.1093/schbul/sbae066.
4
Duration of Untreated Prodromal Psychosis and Cognitive Impairments.未经治疗的前驱期精神病和认知障碍的持续时间。
JAMA Netw Open. 2024 Jan 2;7(1):e2353426. doi: 10.1001/jamanetworkopen.2023.53426.
5
A New Look on Long-COVID Effects: The Functional Brain Fog Syndrome.新冠长期症状的新视角:功能性脑雾综合征
J Clin Med. 2022 Sep 21;11(19):5529. doi: 10.3390/jcm11195529.
精神分裂症阳性与阴性症状量表(PANSS)症状结构的大规模评估。
Asian J Psychiatr. 2021 Aug;62:102732. doi: 10.1016/j.ajp.2021.102732. Epub 2021 Jun 3.
4
An active inference perspective on the negative symptoms of schizophrenia.从主动推理角度看精神分裂症的阴性症状。
Lancet Psychiatry. 2021 Aug;8(8):732-738. doi: 10.1016/S2215-0366(20)30527-7. Epub 2021 Apr 15.
5
Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients.认知洞察力与认知障碍相关,并有助于精神分裂症患者的药物依从性。
Asian J Psychiatr. 2021 Jun;60:102644. doi: 10.1016/j.ajp.2021.102644. Epub 2021 Apr 6.
6
Reinforcement learning abnormalities in the attenuated psychosis syndrome and first episode psychosis.在精神病前期综合征和首发精神病中强化学习异常。
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7
Beyond the cognitive insight paradox: Self-reflectivity moderates the relationship between depressive symptoms and general psychological distress in psychosis.超越认知洞察悖论:在精神病中,自我反思性调节了抑郁症状与一般心理困扰之间的关系。
Schizophr Res. 2020 Aug;222:297-303. doi: 10.1016/j.schres.2020.05.027. Epub 2020 Jun 6.
8
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J Psychiatr Res. 2019 Aug;115:113-120. doi: 10.1016/j.jpsychires.2019.05.008. Epub 2019 May 10.
9
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Schizophr Res. 2018 Dec;202:284-290. doi: 10.1016/j.schres.2018.06.026. Epub 2018 Jun 19.