Dutta Pritika S, Ramdas Nayak Vineetha K, Punja Dhiren
Department of Physiology, All India Institute of Medical Sciences, New Delhi, India.
Dept of Physiology, Manipal TATA Medical College, Jamshedpur, Manipal Academy of Higher Education Manipal, India.
J Taibah Univ Med Sci. 2021 Nov 11;17(3):369-375. doi: 10.1016/j.jtumed.2021.10.002. eCollection 2022 Jun.
The objective of the current study is to investigate the potential of body composition analysis components for predicting coronary artery disease (CAD) in the Type 2 diabetic Asian Indian population.
This case-control study was performed by recruiting 50 type 2 diabetic patients with CAD along with 50 controls. The participants recruited were those between the ages of 40-70 who visited the Department of Cardiology at a tertiary care referral centre in Manipal, India. The diagnosis of CAD was confirmed by electrocardiogram tests and coronary angiogram changes. An anthropometric evaluation was conducted, and body composition analysis was conducted using Bodystat 1500MDD equipment.
In type 2 diabetics, for a unit increase in fat, the odds of CAD increased by 4.43 times. For a unit decrease in lean mass, the odds of CAD increased by 4.98 times. For a unit rise in body fat mass index, the odds of CAD increased by 1.75 times.
In Type 2 diabetics, increased body fat mass with decreased lean tissue mass were valuable markers of CAD. Future studies can examine the benefits of different types of nutritional and exercise interventions targeted at improving muscle mass and reducing fat content in the body with an aim to reduce the occurrence of CAD in patients diagnosed with T2DM.
本研究的目的是调查身体成分分析指标在预测2型糖尿病亚洲印度人群冠状动脉疾病(CAD)方面的潜力。
本病例对照研究通过招募50例患有CAD的2型糖尿病患者和50例对照进行。招募的参与者为年龄在40至70岁之间、前往印度马尼帕尔一家三级医疗转诊中心心脏病科就诊的患者。CAD的诊断通过心电图检查和冠状动脉造影变化得以证实。进行了人体测量评估,并使用Bodystat 1500MDD设备进行了身体成分分析。
在2型糖尿病患者中,脂肪每增加一个单位,患CAD的几率增加4.43倍。瘦体重每减少一个单位,患CAD的几率增加4.98倍。身体脂肪质量指数每升高一个单位,患CAD的几率增加1.75倍。
在2型糖尿病患者中,身体脂肪量增加而瘦组织量减少是CAD的重要标志。未来的研究可以探讨不同类型的营养和运动干预措施在增加肌肉量和减少体内脂肪含量方面的益处,以减少2型糖尿病患者CAD的发生。