Department of General Surgery, Boston Children's Hospital, 300 Longwood Avenue, Fegan 3, Boston, MA 02115, United States.
Department of General Surgery, Boston Children's Hospital, 300 Longwood Avenue, Fegan 3, Boston, MA 02115, United States.
Semin Pediatr Surg. 2022 Jun;31(3):151180. doi: 10.1016/j.sempedsurg.2022.151180. Epub 2022 May 16.
Pediatric patients constitute an important group within the general transplant population, given the opportunity to significantly extend their lives with successful transplantation. Children have historically received special consideration under the various abdominal solid organ allocation algorithms, but matching patients with size and weight restrictions with appropriate donors remains an ongoing issue. Here, we describe the historical trends in pediatric organ allocation policies for liver, kidney, intestine, and pancreas transplantation. We also review recent changes to these allocation policies, with particular attention to recent amendments to geographical prioritization, with the dissolution of donor service areas and United Network for Organ Sharing (UNOS) regions and the subsequent creation of acuity circles.
儿科患者是一般移植人群中的一个重要群体,因为成功移植可以显著延长他们的生命。在各种腹部实体器官分配算法下,儿童历来受到特别考虑,但将符合大小和体重限制的患者与合适的供体相匹配仍然是一个持续存在的问题。在这里,我们描述了肝、肾、肠和胰腺移植的儿科器官分配政策的历史趋势。我们还回顾了这些分配政策的最新变化,特别关注最近对地理优先排序的修订,包括取消供体服务区和器官共享联合网络(UNOS)区域,以及随后创建的严重程度圈。