Xu X L, Wang X, Ma Y L, Zhuang P Y
Department of Voice, Zhongshan Hospital of Xiamen University, Xiamen 361004, China.
School of Medicine, Xiamen University, Xiamen 361005, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Jun 7;57(6):706-710. doi: 10.3760/cma.j.cn115330-20220329-00141.
To analyze the characteristics of vocal fold vibration of normal people and patients with spasmodic dysphonia (SD) using laryngeal high speed videoendoscopy combined with glottal area wave analysis. This prospective study examined twenty healthy subjects (10 males and 10 females), 12 patients with adductor spasmodic dysphonia(AdSD) (2 males,10 females)as AdSD group and 2 patients with abductor spasmodic dysphonia(AbSD) (2 males) as AbSD group. Twelve of healthy subjects (2 males,10 females) were selected as control group according to AdSD group gender match. All the subjects were recruited from the Department of Voice, Zhongshan Hospital, Xiamen University from October 2019 to December 2020. All subjects underwent laryngeal high speed videoendoscopy and 10 vibration periods were selected from each recording and were used to quantitatively analyze the change of glottal area and vocal fold vibration parameters (Speed Quotient (SQ), Open Quotient (OQ) and Close Quotient (CQ)). 1. There were statistically significant differences in SQ, CQ and OQ between males and females in the healthy subjects (=12.28, 5.59, 5.59, <0.05). The change of the glottal area during each vibration period in healthy subjects was relatively stable(0.19-0.42). 2. The change of the glottal area during each vibration period in AdSD subjects had larger fluctuations, with the glottal area change index fluctuating in the range of 0.31 to 0.62. The SQ value of the AdSD group was significantly lower than that of control group (=4.246, <0.05). There were no significant differences in OQ and CQ between AdSD group and normal group (=1.064, 1.332, >0.05); The SQ value of the AbSD group tended to increase compared to normal group. Laryngeal high speed videoendoscopy combined with glottal area wave analysis has a certain reference value in the studying the vibration characteristics of SD patients. SQ has good specificity.
采用喉高速视频内镜结合声门面积波分析，分析正常人及痉挛性发声障碍（SD）患者的声带振动特征。本前瞻性研究纳入了20名健康受试者（10名男性和10名女性）、12名内收型痉挛性发声障碍（AdSD）患者（2名男性，10名女性）作为AdSD组，以及2名外展型痉挛性发声障碍（AbSD）患者（2名男性）作为AbSD组。根据AdSD组的性别匹配情况，从健康受试者中选取12名（2名男性，10名女性）作为对照组。所有受试者均于2019年10月至2020年12月从厦门大学附属中山医院嗓音科招募。所有受试者均接受喉高速视频内镜检查，从每次记录中选取10个振动周期，用于定量分析声门面积和声带振动参数（速度商（SQ）、开放商（OQ）和闭合商（CQ））的变化。1. 健康受试者中，男性和女性的SQ、CQ和OQ存在统计学显著差异（=12.28, 5.59, 5.59, <0.05）。健康受试者每个振动周期内声门面积的变化相对稳定（0.19 - 0.42）。2. AdSD受试者每个振动周期内声门面积的变化波动较大，声门面积变化指数在0.31至0.62范围内波动。AdSD组的SQ值显著低于对照组（=4.246, <0.05）。AdSD组与正常组的OQ和CQ无显著差异（=1.064, 1.332, >0.05）；AbSD组的SQ值与正常组相比有升高趋势。喉高速视频内镜结合声门面积波分析在研究SD患者的振动特征方面具有一定参考价值。SQ具有良好的特异性。
