Addington E E, Grunewald K K
J Nutr. 1987 Mar;117(3):593-7. doi: 10.1093/jn/117.3.593.
Male Wistar rats (n = 72) trained to run on a treadmill were fasted overnight and fed by gavage 3 ml unsupplemented water or a solution containing 2 g of glucose, fructose or sucrose 30 min prior to exercise. Six rats from each dietary group were killed after 0, 1 or 2 h of exercise. Blood glucose levels decreased in all groups over the 2-h exercise period; however, the largest decline in blood glucose was exhibited by the rats fed unsupplemented water (-32.1%), followed by those fed fructose (-26.9%), sucrose (-13.9%) and glucose (-8.3%). The water-fed control rats also had the largest increase in circulating free fatty acids (+215.4%), followed by those fed fructose (+120.8%), sucrose (+69.2%) and glucose (+57.5%). The fructose-fed animals exhibited the greatest depletion of liver glycogen and the smallest decline in soleus and red vastus lateralis muscle glycogen of the rats fed the different carbohydrates. The data indicate that exercise-induced changes in substrate levels can be modified by the type of carbohydrate given prior to exercise.
将经过训练能在跑步机上跑步的雄性Wistar大鼠（n = 72）隔夜禁食，在运动前30分钟通过灌胃给予3毫升无添加物的水或含有2克葡萄糖、果糖或蔗糖的溶液。每个饮食组的6只大鼠在运动0、1或2小时后处死。在2小时的运动期间，所有组的血糖水平均下降；然而，血糖下降幅度最大的是给予无添加物水的大鼠（-32.1%），其次是给予果糖的大鼠（-26.9%）、蔗糖的大鼠（-13.9%）和葡萄糖的大鼠（-8.3%）。给予水的对照大鼠循环游离脂肪酸的增加幅度也最大（+215.4%），其次是给予果糖的大鼠（+120.8%）、蔗糖的大鼠（+69.2%）和葡萄糖的大鼠（+57.5%）。给予果糖的动物肝糖原消耗最大，而在给予不同碳水化合物的大鼠中，比目鱼肌和股外侧肌红色部分的糖原下降幅度最小。数据表明，运动诱导的底物水平变化可通过运动前给予的碳水化合物类型进行调节。
