运动或禁食后，葡萄糖或果糖喂养对肌肉和肝脏糖原补充的影响。

Effects of glucose or fructose feeding on glycogen repletion in muscle and liver after exercise or fasting.

作者信息

Conlee R K, Lawler R M, Ross P E

出版信息

Ann Nutr Metab. 1987;31(2):126-32. doi: 10.1159/000177259.

Abstract

In athletics, muscle and liver glycogen content is critical to endurance. This study compared the effectiveness of glucose and fructose feeding on restoring glycogen content after glycogen was decreased by exercise (90-min swim) or fasting (24 h). After 2 h of recovery from either exercise or fasting there was no measurable glycogen repletion in red vastus lateralis muscle in response to fructose. In contrast, glucose feeding induced a similar and significant carbohydrate storage after both depletion treatments (8.44 mumol X g-1 X 2 h-1). In the liver, following 2 h of recovery, the rates of glycogen storage were similar after either glucose or fructose ingestion, but fasting caused a greater rate of repletion (83 mumol X g-1 X 2 h-1) than exercise (50 mumol X g-1 X 2 h-1). After 4 h of recovery fructose-fed exercised animals had the highest glycogen concentration (165 mumol X g-1) followed by the glucose-fed exercised group (119 mumol X g-1). These values were 50 and 36%, respectively, of that measured in the normal-fed liver (327 mumol X g-1). In contrast, liver glycogen values in the fasted group decreased between the 2nd and 4th hour of recovery in response to both feeding regimens. From these results we conclude that fructose is a poor nutritional precursor for rapid glycogen restoration in muscle after exercise, but that both glucose and fructose promote rapid accumulation of glycogen in the liver.

摘要

在田径运动中，肌肉和肝脏中的糖原含量对耐力至关重要。本研究比较了在糖原因运动（90分钟游泳）或禁食（24小时）而减少后，摄入葡萄糖和果糖对恢复糖原含量的效果。从运动或禁食中恢复2小时后，外侧股四头肌对果糖没有可测量的糖原补充反应。相比之下，在两种消耗处理后，摄入葡萄糖均诱导了相似且显著的碳水化合物储存（8.44 μmol·g⁻¹·2 h⁻¹）。在肝脏中，恢复2小时后，摄入葡萄糖或果糖后的糖原储存速率相似，但禁食导致的补充速率（83 μmol·g⁻¹·2 h⁻¹）高于运动（50 μmol·g⁻¹·2 h⁻¹）。恢复4小时后，喂食果糖的运动动物糖原浓度最高（165 μmol·g⁻¹），其次是喂食葡萄糖的运动组（119 μmol·g⁻¹）。这些值分别是正常喂食肝脏中测量值（327 μmol·g⁻¹）的50%和36%。相比之下，禁食组的肝脏糖原值在恢复的第2小时至第4小时之间，对两种喂食方案均有所下降。从这些结果我们得出结论，运动后果糖作为快速恢复肌肉糖原的营养前体较差，但葡萄糖和果糖都能促进肝脏中糖原的快速积累。