Ahlhelm F J, Tarnutzer A A, Shariat K
Abteilung Neuroradiologie, Zentrum für Bildgebung, Kantonsspital Baden AG, Im Ergel 1, 5404, Baden, Schweiz.
Neurologie, Kantonsspital Baden AG, Baden, Schweiz.
Radiologie (Heidelb). 2022 Aug;62(8):648-653. doi: 10.1007/s00117-022-01028-0. Epub 2022 Jun 20.
CLINICAL/METHODICAL ISSUE: Cavernous malformations or cavernomas belong to the angiodysplasias. They may be sporadic or familial and cause symptoms (epilepsy) despite the absence of a left-to-right shunt. In addition to intracranial locations, spinal cavernomas are also found.
Magnetic resonance imaging (MRI) and computed tomography (CT) are used for diagnosis PERFORMANCE: MRI, except for acutely or subacutely hemorrhaged cavernomas, is superior to CT for lesion detection.
CT is reserved for acute diagnosis. MRI, especially susceptibility-sensitive gradient echo sequences, can also detect cavernomas without (sub-)acute hemorrhage or calcifications.
MRI is also useful for differentiating the familial form vs. sporadic form. Digital subtraction angiography (DSA) is used for differential diagnosis in rare cases, as cavernomas show no correlate here.
临床/方法学问题:海绵状血管畸形或海绵状瘤属于血管发育异常。它们可能是散发性的或家族性的,即使没有左向右分流也会引起症状(癫痫)。除了颅内部位,也发现有脊髓海绵状瘤。
磁共振成像(MRI)和计算机断层扫描(CT)用于诊断。性能:除了急性或亚急性出血性海绵状瘤外,MRI在病变检测方面优于CT。
CT用于急性诊断。MRI,尤其是敏感性梯度回波序列,也可以检测出无(亚)急性出血或钙化的海绵状瘤。
MRI对于区分家族性形式和散发性形式也很有用。数字减影血管造影(DSA)在罕见情况下用于鉴别诊断,因为海绵状瘤在此处无相关性表现。