State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 130022, Changchun, China.
University of Science and Technology of China, 230026, Hefei, China.
Angew Chem Int Ed Engl. 2022 Aug 15;61(33):e202207425. doi: 10.1002/anie.202207425. Epub 2022 Jul 8.
The inherently tenuous adhesion strength and limited environmental tolerance of supramolecular adhesives severely restrict their application scenarios. It is challenging for the development of robust adhesives with extreme temperature tolerance. Herein, we report a new type of temperature-resistant crown-ether-protein (CEP) adhesive by harnessing synergistic host-guest molecular interactions between engineered crown ether and protein building blocks. The outputs of CEP adhesive demonstrate ultrahigh shearing adhesion strength of ≈22 MPa over a wide temperature range from -196 to 200 °C, superior to other established supramolecular or polymeric adhesives. The temperature-induced phase transition and internal bound water stabilized the system and led to superb adhesion under extreme conditions. Thus, this work pioneers a molecular engineering approach for the generation of adhesives with tailored applications in extreme settings.
超分子粘合剂的固有粘附强度较弱，环境耐受性有限，严重限制了它们的应用场景。开发具有极端耐温性的坚固粘合剂具有挑战性。在此，我们通过利用工程化冠醚和蛋白质构建块之间的协同主客体分子相互作用，报告了一种新型的耐温冠醚-蛋白质（CEP）粘合剂。CEP 粘合剂的输出表现出超高温剪切粘附强度，在从-196 到 200°C 的很宽的温度范围内≈22 MPa，优于其他已建立的超分子或聚合物粘合剂。温度诱导的相转变和内部结合水稳定了该体系，并在极端条件下实现了优异的粘附性。因此，这项工作开创了一种分子工程方法，用于生成具有在极端环境中定制应用的粘合剂。
