Department of Applied Health Science, Indiana University School of Public Health Bloomington, Bloomington, Indiana, U.S.A.
Department of Epidemiology and Biostatistics, Indiana University School of Public Health Bloomington, Bloomington, Indiana, U.S.A.
J Am Coll Health. 2024 Jul;72(5):1592-1598. doi: 10.1080/07448481.2022.2086010. Epub 2022 Jun 21.
This longitudinal study tested the relationship between cigarette and e-cigarette use and SARS-CoV-2 seroconversion among US college students.
Undergraduate students (n = 764), drawn from a randomly selected invitation-only pool from a large Midwestern university, that were initially negative for SARS-CoV-2 antibodies and were re-tested in November were included in this study conducted in Fall 2020.
Demographics and cigarette and e-cigarette use behaviors (nicotine use) were collected in a baseline survey. SARS-CoV-2 antibody tests were administered in September (baseline) and November (endline) of 2020. Log-binomial regression analyses were conducted to test the association between nicotine use and SARS-CoV-2 seroconversion.
SARS-CoV-2 seroconversion was 5.2%. No statistically significant associations were found between nicotine use and SARS-CoV-2 seroconversion.
Contrary to prior results, we found no association between nicotine use and SARS-CoV-2 seroconversion. Nicotine use may not be a key risk factor for COVID-19 acquisition in predominantly healthy college-aged populations.
本纵向研究检验了美国大学生吸烟和使用电子烟与 SARS-CoV-2 血清转化之间的关系。
本研究纳入了 2020 年秋季进行的一项研究，从一所中西部大型大学的随机邀请池中抽取了本科生（n=764），这些学生最初 SARS-CoV-2 抗体检测呈阴性，并于 11 月再次进行检测。
在基线调查中收集了人口统计学数据和吸烟及电子烟使用行为（尼古丁使用）。2020 年 9 月（基线）和 11 月（期末）进行了 SARS-CoV-2 抗体检测。采用对数二项式回归分析检验尼古丁使用与 SARS-CoV-2 血清转化率之间的关联。
SARS-CoV-2 血清转化率为 5.2%。尼古丁使用与 SARS-CoV-2 血清转化率之间无统计学显著关联。
与先前的结果相反，我们发现尼古丁使用与 SARS-CoV-2 血清转化率之间没有关联。在以健康的大学生为主的人群中，尼古丁使用可能不是 COVID-19 感染的关键风险因素。
