Public Health Physician, Hawke's Bay District Health Board, Hastings 4156, New Zealand.
Clinical Director, Health Improvement and Equity Directorate, Hawke's Bay District Health Board, Hastings 4156, New Zealand.
N Z Med J. 2021 Dec 17;134(1547):71-84.
In August 2016, a large waterborne campylobacteriosis outbreak occurred in Havelock North, New Zealand. This analysis describes the clinical complications of cases admitted to hospital as a result of acute infection, identifies risk factors for hospitalisation and compares deaths between hospitalised and non-hospitalised cases. Hospital admissions with post-infectious sequelae were excluded as they are the subject of a separate analysis.
A case series analysis was undertaken by reviewing the electronic medical records of 933 residents of Hawke's Bay District Health Board with probable and confirmed campylobacteriosis linked to the Havelock North Campylobacter outbreak.
A total of 67 hospital admissions, among 58 individuals, are described. Pre-existing comorbidity and advanced age were significant risk factors for hospital admission in univariate analysis. Dehydration (74.1%), electrolyte imbalance (35.8%) and acute kidney injury (27.6%) were common among hospitalised cases. The proportion of hospitalised cases that died within one year was significantly higher when compared to deaths among non-hospitalised cases (OR 5.0, 95% CI: 2.3-10.7), although this trend was not statistically significant after adjusting for age and comorbidity (OR 2.3, 95% CI: 0.96-5.3).
This study highlights the serious health impacts that occurred from a campylobacteriosis outbreak of this magnitude.
2016 年 8 月，新西兰黑斯廷斯北部发生了一起大规模的水源性弯曲杆菌病暴发。本分析描述了因急性感染而住院的病例的临床并发症，确定了住院的危险因素，并比较了住院和非住院病例的死亡情况。因感染后后遗症而住院的病例被排除在外，因为它们是另一项分析的主题。
通过回顾哈夫洛克北弯曲杆菌暴发相关的霍克湾地区卫生局 933 名疑似和确诊弯曲杆菌病居民的电子病历，对 933 名居民进行了病例系列分析。
共描述了 58 名患者中的 67 例住院病例。在单变量分析中，预先存在的合并症和高龄是住院的显著危险因素。脱水（74.1%）、电解质失衡（35.8%）和急性肾损伤（27.6%）在住院病例中较为常见。与非住院病例相比，住院病例在一年内死亡的比例显著更高（OR 5.0，95%CI：2.3-10.7），但在校正年龄和合并症后（OR 2.3，95%CI：0.96-5.3），这一趋势并不显著。
本研究强调了如此大规模的弯曲杆菌病暴发所带来的严重健康影响。
