Exercise Medicine Clinic-CLINIMEX, Rio de Janeiro, Brazil
Exercise Medicine Clinic-CLINIMEX, Rio de Janeiro, Brazil.
Br J Sports Med. 2022 Sep;56(17):975-980. doi: 10.1136/bjsports-2021-105360. Epub 2022 Jun 21.
Balance quickly diminishes after the mid-50s increasing the risk for falls and other adverse health outcomes. Our aim was to assess whether the ability to complete a 10- s one-legged stance (10-second OLS) is associated with all-cause mortality and whether it adds relevant prognostic information beyond ordinary demographic, anthropometric and clinical data.
Anthropometric, clinical and vital status and 10-s OLS data were assessed in 1702 individuals (68% men) aged 51-75 years between 2008 and 2020. Log-rank and Cox modelling were used to compare survival curves and risk of death according to ability (YES) or inability (NO) to complete the 10-s OLS test.
Overall, 20.4% of the individuals were classified as NO. During a median follow-up of 7 years, 7.2% died, with 4.6% (YES) and 17.5% (NO) on the 10-s OLS. Survival curves were worse for NO 10-s OLS (log-rank test=85.6; p<0.001). In an adjusted model incorporating age, sex, body mass index and comorbidities, the HR of all-cause mortality was higher (1.84 (95% CI: 1.23 to 2.78) (p0.001)) for NO individuals. Adding 10-s OLS to a model containing established risk factors was associated with significantly improved mortality risk prediction as measured by differences in -2 log likelihood and integrated discrimination improvement.
Within the limitations of uncontrolled variables such as recent history of falls and physical activity, the ability to successfully complete the 10-s OLS is independently associated with all-cause mortality and adds relevant prognostic information beyond age, sex and several other anthropometric and clinical variables. There is potential benefit to including the 10-s OLS as part of routine physical examination in middle-aged and older adults.
50 多岁以后，平衡能力迅速下降，增加了跌倒和其他不良健康后果的风险。我们的目的是评估能否完成 10 秒单腿站立（10 秒 OLS）与全因死亡率相关，以及它是否在普通人口统计学、人体测量学和临床数据之外提供相关预后信息。
评估了 2008 年至 2020 年间 1702 名年龄在 51-75 岁之间的个体（68%为男性）的人体测量学、临床和生命状态以及 10 秒 OLS 数据。使用对数秩和 Cox 模型比较根据能否（是）完成 10 秒 OLS 测试（是）或不能（否）完成 10 秒 OLS 测试的生存曲线和死亡风险。
总体而言，20.4%的个体被归类为否。在中位数为 7 年的随访期间，有 7.2%的人死亡，其中 4.6%（是）和 17.5%（否）在 10 秒 OLS 上。不能完成 10 秒 OLS 的生存曲线更差（对数秩检验=85.6；p<0.001）。在包含年龄、性别、体重指数和合并症的调整模型中，全因死亡率的 HR 更高（1.84（95%CI：1.23 至 2.78）（p<0.001））。将 10 秒 OLS 添加到包含既定危险因素的模型中，与死亡率风险预测的显著改善相关，这可以通过 -2 对数似然和综合鉴别改善的差异来衡量。
在无法控制跌倒和体力活动等近期史等变量的限制下，成功完成 10 秒 OLS 与全因死亡率独立相关，并在年龄、性别和其他几个人体测量学和临床变量之外提供了相关预后信息。将 10 秒 OLS 作为中年和老年人常规体检的一部分可能具有潜在益处。
