Iacovelli V, Carilli M, Sandri M, Forte V, Cipriani C, Bertolo R, Vittori M, Petta F, Maiorino F, Signoretti M, Antonucci M, Cavallo A U, Sperandio M, Finazzi Agrò E, Bove P
Department of Urology, San Carlo di Nancy Hospital, Rome, Italy.
Big & Open Data Innovation Laboratory (BODaI-Lab), University of Brescia, Brescia, Italy.
Prostate Cancer Prostatic Dis. 2023 Jun;26(2):374-378. doi: 10.1038/s41391-022-00563-0. Epub 2022 Jun 21.
To explore the role of preoperative MRI prostate shape in urinary incontinence after robot-assisted radical prostatectomy (RARP).
Patients were stratified into four groups based on the mpMRI prostatic apex shape: Group A (prostatic apex overlapping the membranous urethra anteriorly and posteriorly), Group B and C (overlap of the prostatic apex of the anterior or posterior membranous urethra, respectively) and Group D (no overlap). Preoperative variables and intraoperative data were compared. Continence recovery was defined as no pad/day or 1 safety pad/day by an outpatient evaluation performed at 1, 3, 6, and 12 months after RARP.
One hundred patients underwent RARP were classified as belonging to Group A (n = 30), Group B (n = 16), Group C (n = 14), and Group D (n = 40). Group D showed a significantly more favorable urinary continence recovery after RARP respect to all the other shapes presenting any forms of overlapping (HR = 1.9, 95% CI 1.2-3.1, p = 0.007). The estimated HR remained substantially unchanged after adjusting by age, body mass index, CCI, prostate volume, and bladder neck sparing (HR = 1.9, 95% CI 1.1-3.2, p = 0.016). The continence recovery median time was 9 months for Group A + B + C (95% CI 5-11) and 4 months for Group D (95% CI 2-6) (p = 0.023).
Shape D showed a better continence recovery when compared to other shapes presenting any kind of overlapping of the prostatic apex over the membranous urethra.
探讨术前MRI前列腺形态在机器人辅助根治性前列腺切除术(RARP)后尿失禁中的作用。
根据mpMRI前列腺尖部形态将患者分为四组:A组(前列腺尖部前后均与膜性尿道重叠)、B组和C组(分别为前列腺尖部与膜性尿道前部或后部重叠)以及D组(无重叠)。比较术前变量和术中数据。通过RARP术后1、3、6和12个月进行的门诊评估,将控尿恢复定义为无需使用尿垫/天或1个安全尿垫/天。
100例行RARP的患者被分为A组(n = 30)、B组(n = 16)、C组(n = 14)和D组(n = 40)。与呈现任何形式重叠的其他形态相比,D组在RARP术后显示出明显更有利的尿控恢复(HR = 1.9,95%CI 1.2 - 3.1,p = 0.007)。在根据年龄、体重指数、CCI、前列腺体积和保留膀胱颈进行调整后,估计的HR基本保持不变(HR = 1.9,95%CI 1.1 - 3.2,p = 0.016)。A组+B组+C组的控尿恢复中位时间为9个月(95%CI 5 - 11),D组为4个月(95%CI 2 - 6)(p = 0.023)。
与前列腺尖部在膜性尿道上呈现任何重叠的其他形态相比,D形态显示出更好的控尿恢复。