中性粒细胞-淋巴细胞比值和血小板-淋巴细胞比值在决定接受血浆置换的重症监护患者的死亡率方面是否起作用？单中心经验。
Do neutrophil-lymphocyte ratio and platelet-lymphocyte ratio have a role in determining mortality in intensive care patients undergoing plasmapheresis? Single-center experience.
机构信息
Department of Internal Medicine, Haematology, Istanbul Medipol University School of Medicine, Istanbul, Turkey.
Department of Anesthesiology and Reanimation, Istanbul Medipol University School of Medicine, Istanbul, Turkey.
出版信息
Ther Apher Dial. 2023 Feb;27(1):146-151. doi: 10.1111/1744-9987.13900. Epub 2022 Jul 4.
INTRODUCTION
Plasmapheresis is a frequently used procedure that removes the pathogenic components from circulation. We aimed to evaluate the relationship between plasmapheresis, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and mortality in the intensive care unit (ICU) between 2014 and 2021.
METHODS
Forty-nine patients (27 females and 22 males) were included. Demographic characteristics, laboratory values of the day of admittance to the ICU, APACHE II scores, and length of stay were recorded.
RESULTS
The mean age was 52.73 ± 16.93. APACHE II value (p = 0.003; p < 0.01), NLR ratio (p = 0.001; p < 0.01) and PLR ratio (p = 0.001; p < 0.01) of the surviving group were lower than those of the deceased group, which was statistically significant.
CONCLUSION
As high PLR and NLR levels suggest increased mortality in the ICU population, attention should be paid for increased NLR and PLR when plasmapheresis is decided on in the ICU.
介绍
血浆置换是一种从循环中去除致病成分的常用方法。我们旨在评估 2014 年至 2021 年间 ICU 中血浆置换、中性粒细胞-淋巴细胞比值（NLR）、血小板-淋巴细胞比值（PLR）与死亡率之间的关系。
方法
共纳入 49 例患者（女性 27 例，男性 22 例）。记录人口统计学特征、入住 ICU 当天的实验室值、APACHE II 评分和住院时间。
结果
平均年龄为 52.73±16.93 岁。存活组的 APACHE II 值（p=0.003；p<0.01）、NLR 比值（p=0.001；p<0.01）和 PLR 比值（p=0.001；p<0.01）均低于死亡组，差异有统计学意义。
结论
由于高 PLR 和 NLR 水平表明 ICU 人群死亡率增加，因此在 ICU 决定进行血浆置换时应注意 NLR 和 PLR 的增加。
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