Department of Medicine, Addiction Medicine Unit, Verona University Hospital, 37134 Verona, Italy.
a:1:{s:5:"en_US";s:146:"Unit of Addiction Medicine, Department of Internal Medicine, Integrated University Hospital of Verona, Policlinico "G.B. Rossi", Verona, Italy";}.
Acta Biomed. 2022 Jun 22;93(S1):e2022073. doi: 10.23750/abm.v93iS1.12450.
Cytisine is considered to be the oldest medication for smoking cessation and has been used for this purpose in some Eastern/Central European and Central Asian countries for over 50 years. Several sources points towards cytisine's efficacy and effectiveness; it's well tolerated when taken at the recommended dose, and adverse events reported in trials are typically non-serious and self-limiting gastrointestinal and sleep disturbances. We report a suspect case of urticaria during treatment for smoking cessation with cytisine in a woman of 48 years treated for smoking at the Unit of Addiction Medicine, Department of Internal Medicine, Hospital Trust of Verona, Italy. The therapeutic protocol of cytisine that was used is of the "inductive" type; it consists in gradually increasing the daily capsules taken, with a parallel reduction in the number of cigarettes smoked until complete cessation between the fifth and ninth day of therapy (quit day) The number of capsules taken is then gradually reduced. She was treated for the firsts three days with betamethasone 1 mg/die, on the advice of her general practitioner, and suspended Cytisine. A week later the patient showed signs of recovery.
烟碱是被认为是最古老的戒烟药物，在一些东欧、中欧和中亚国家已经使用了超过 50 年。有几个来源指出了烟碱的疗效和有效性；在推荐剂量下使用时，它的耐受性良好，试验中报告的不良事件通常是非严重的，且自我限制的胃肠道和睡眠障碍。我们报告了一例疑诊的荨麻疹病例，该病例发生在意大利维罗纳医院信托的内科成瘾医学科，一名 48 岁女性因吸烟而使用烟碱戒烟治疗。使用的烟碱治疗方案是“诱导”型的；它包括逐渐增加每天服用的胶囊数量，同时减少吸烟数量，直到治疗第 5 天至第 9 天（戒烟日）完全停止吸烟。然后逐渐减少胶囊的数量。根据她的全科医生的建议，她在前三天接受了 1 毫克/天的倍他米松治疗，并暂停了烟碱治疗。一周后，患者出现了康复迹象。
