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制药生产中新兴技术的可持续性。

The sustainability of emerging technologies for use in pharmaceutical manufacturing.

作者信息

Weaver Edward, O'Hagan Collette, Lamprou Dimitrios A

机构信息

School of Pharmacy, Queen's University Belfast, Belfast, UK.

出版信息

Expert Opin Drug Deliv. 2022 Jul;19(7):861-872. doi: 10.1080/17425247.2022.2093857. Epub 2022 Jun 27.

DOI:10.1080/17425247.2022.2093857
PMID:35732275
Abstract

INTRODUCTION

Sustainability within the pharmaceutical industry is becoming a focal point for many companies, to improve the longevity and social perception of the industry. Both additive manufacturing (AM) and microfluidics (MFs) are continuously progressing, so are far from their optimization in terms of sustainability; hence, it is the aim of this review to highlight potential gaps alongside their beneficial features. Discussed throughout this review also will be an in-depth discussion on the environmental, legal, economic, and social particulars relating to these emerging technologies.

AREAS COVERED

Additive manufacturing (AM) and microfluidics (MFs) are discussed in depth within this review, drawing from up-to-date literature relating to sustainability and circular economies. This applies to both technologies being utilized for therapeutic and analytical purposes within the pharmaceutical industry.

EXPERT OPINION

It is the role of emerging technologies to be at the forefront of promoting a sustainable message by delivering plausible environmental standards whilst maintaining efficacy and economic viability. AM processes are highly customizable, allowing for their optimization in terms of sustainability, from reducing printing time to reducing material usage by removing supports. MFs too are supporting sustainability via reduced material wastage and providing a sustainable means for point of care analysis.

摘要

引言

制药行业的可持续发展正成为许多公司关注的焦点,以提高该行业的存续时间和社会认知度。增材制造(AM)和微流控技术(MFs)都在不断发展,但在可持续性方面远未达到优化状态;因此,本综述旨在突出它们的潜在差距及其有益特性。本综述还将深入讨论与这些新兴技术相关的环境、法律、经济和社会细节。

涵盖领域

本综述深入讨论了增材制造(AM)和微流控技术(MFs),参考了与可持续性和循环经济相关的最新文献。这适用于制药行业中用于治疗和分析目的的这两种技术。

专家观点

新兴技术的作用是通过提供合理的环境标准,同时保持有效性和经济可行性,在推动可持续发展理念方面走在前列。增材制造工艺具有高度可定制性,可在可持续性方面进行优化,从减少打印时间到通过去除支撑结构减少材料使用。微流控技术也通过减少材料浪费和提供即时护理分析的可持续手段来支持可持续发展。

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