Douw Linda, Senden Mario, van den Heuvel Martijn
Department of Anatomy and Neurosciences, Amsterdam Neuroscience, UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.
Netw Neurosci. 2022 Jun 1;6(2):298-300. doi: 10.1162/netn_e_00249. eCollection 2022 Jun.
There is an ongoing need for novel biomarkers in clinical neuroscience, as diagnosis of neurological and psychiatric disorders is hampered by the pronounced overlap of behavioral symptoms and other pathophysiological characteristics. The question that this Focus Feature puts center stage is whether network-based biomarkers may provide a viable tool for distinguishing between disordered populations or whether they may yield only limited differentiating power because of largely shared network characteristics across conditions.
临床神经科学领域对新型生物标志物的需求一直存在,因为神经和精神疾病的诊断受到行为症状和其他病理生理特征明显重叠的阻碍。本聚焦专题重点探讨的问题是,基于网络的生物标志物是否可能成为区分疾病群体的可行工具,或者由于不同疾病状态下网络特征在很大程度上存在共享,它们是否只能产生有限的区分能力。