由耐克拉霉素的鸟分枝杆菌肺病引起的伴有气胸的胸膜炎

Pleurisy with pneumothorax due to CAM-resistant MAC lung disease.

作者信息

Nukui Yoshihisa, Kawahara Tatsuo, Hanzawa Satoshi

机构信息

Department of Respiratory Medicine Shuuwa General Hospital Saitama Japan.

出版信息

Respirol Case Rep. 2022 Jun 14;10(7):e0993. doi: 10.1002/rcr2.993. eCollection 2022 Jul.

DOI:10.1002/rcr2.993

PMID:35734552

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9195571/

Abstract

A 72-year-old man received rifampicin, ethambutol and sitafloxacin to treat clarithromycin (CAM)-resistant complex (MAC) lung disease. He was admitted because of fever. Pneumothorax and pleural effusion were present in the right lung, and a new consolidation appeared in the right upper lobe. Based on positive culture of the pleural effusion for CAM-resistant and findings on chest computed tomography, he was diagnosed with pleurisy due to , with rupture of the subpleural lung parenchymal lesion into the pleural space. Additional treatment with streptomycin (SM) improved the patient's high-grade fever. SM might be effective for pleurisy caused by CAM-resistant MAC lung disease.

摘要

一名72岁男性接受利福平、乙胺丁醇和西他沙星治疗耐克拉霉素（CAM）的鸟分枝杆菌复合群（MAC）肺病。他因发热入院。右肺存在气胸和胸腔积液，右上叶出现新的实变。根据胸腔积液对耐CAM菌的培养阳性结果及胸部计算机断层扫描结果，他被诊断为耐CAM菌所致胸膜炎，胸膜下肺实质病变破裂进入胸腔。加用链霉素（SM）治疗改善了患者的高热。SM可能对耐CAM菌的MAC肺病所致胸膜炎有效。