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不育男性精索静脉曲张手术治疗的功能结局:三种技术的比较。

Functional outcomes of surgical treatment of varicocele in infertile men: Comparison of three techniques.

作者信息

Ouanes Yassine, Rahoui Moez, Chaker Kays, Marrak Mahdi, Bibi Mokhtar, Mrad Dali Kheireddine, Sellami Ahmed, Ben Rhouma Sami, Nouira Yassine

机构信息

Urology Department, La Rabta Hospital, Tunis, Tunisia.

出版信息

Ann Med Surg (Lond). 2022 Jun 4;78:103937. doi: 10.1016/j.amsu.2022.103937. eCollection 2022 Jun.

Abstract

INTRODUCTION

Among identified causes of male infertility, varicocele holds an important place and is significantly associated with sperm quality deterioration. Surgical management of this condition leads to an improvement in the sperm count and an increase in the spontaneous pregnancy rate.

OBJECTIVE

The goal of this study was to compare different surgical techniques in terms of morbidity and fertility results.

PATIENTS AND METHODS

It is a retrospective study of interesting patients followed for infertility related to varicocele between January 2007 and December 2015. Three surgical techniques were compared: open inguinal surgery, antegrade sclerotherapy, and laparoscopy. Morbidity and pregnancy rate were assessed according to different techniques.

RESULTS

Post-operative complication rates were comparable (p = 0,94) between the 3 surgical techniques. An amelioration of sperm parameters has been noted in all operated patients, without statistical difference between the three techniques (p = 0,29 for the sperm concentration and p = 0,49 for the progressive mobility). Spontaneous pregnancy was better (p = 0,03) for patients who have had a varicocelectomy in a sub-inguinal way.

CONCLUSION

All of the three surgical techniques used in this study showed an improvement of sperm parameters in an equal way with similar morbidity. However, the spontaneous pregnancy rate with open surgery was better.

摘要

引言

在已确定的男性不育原因中,精索静脉曲张占据重要地位,且与精子质量恶化显著相关。对此病症的手术治疗可使精子数量增加,自然受孕率提高。

目的

本研究旨在比较不同手术技术在发病率和生育结果方面的差异。

患者与方法

这是一项回顾性研究,研究对象为2007年1月至2015年12月期间因精索静脉曲张相关不育而接受随访的患者。比较了三种手术技术:开放腹股沟手术、顺行硬化疗法和腹腔镜手术。根据不同技术评估发病率和妊娠率。

结果

三种手术技术的术后并发症发生率相当(p = 0.94)。所有接受手术的患者精子参数均有改善,三种技术之间无统计学差异(精子浓度p = 0.29,进行性活动率p = 0.49)。采用腹股沟下精索静脉结扎术的患者自然受孕情况更好(p = 0.03)。

结论

本研究中使用的所有三种手术技术均以相似的发病率同等程度地改善了精子参数。然而,开放手术的自然受孕率更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b524/9207144/44120860d271/gr1.jpg

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