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多发性原发性肺脑膜瘤:一例病例报告并文献复习。

Multiple primary pulmonary meningioma: A case report and literature review.

机构信息

Department of Thoracic Surgery, Chengdu Third People's Hospital, the Affiliated Hospital of Southwest Jiaotong University, Chendu, China.

出版信息

Thorac Cancer. 2022 Aug;13(15):2257-2259. doi: 10.1111/1759-7714.14542. Epub 2022 Jun 22.

Abstract

Lung cancer has become a leading cause of cancer-related deaths. With the conventional use of low-dose spiral computed tomography (CT) in physical examinations, an increasing number of small pulmonary nodules are screened. However, primary pulmonary meningiomas (PPMs) are rarely reported. Here, we report the case of a 64-year-old woman who had a CT scan during physical examination, which revealed three ground-glass-like opacity pulmonary nodules in both lungs. The patient underwent video-assisted thoracoscopic wedge resection of the right upper and lower lobes. Paraffin sections revealed pulmonary meningothelial-like and collagenous nodules in the right upper and lower lobes which stained as follows: EMA+, VIM+, SMA-, S-100-, CD34-, STAT6-, Ki-67+ (2%), and CgA-. Primary pulmonary meningiomas (PPMs) were finally diagnosed. PPM is a kind of rare and benign tumor. Surgery can provide a precise pathological examination, and patients can achieve an excellent prognosis after surgical resection.

摘要

肺癌已成为癌症相关死亡的主要原因。随着低剂量螺旋 CT 在体检中的常规应用,越来越多的小肺结节被筛选出来。然而,原发性肺脑膜瘤(PPM)很少见。在这里,我们报告了一例 64 岁女性的病例,她在体检时进行了 CT 扫描,显示双肺有三个磨玻璃样密度的肺结节。患者接受了电视辅助胸腔镜下右上叶和下叶楔形切除术。石蜡切片显示右上叶和下叶有肺脑膜内皮样和胶原性结节,免疫组化结果如下:EMA+、VIM+、SMA-、S-100-、CD34-、STAT6-、Ki-67+(2%)和 CgA-。最终诊断为原发性肺脑膜瘤(PPM)。PPM 是一种罕见的良性肿瘤。手术可以提供精确的病理检查,患者在手术后可以获得极好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7df2/9346167/78d01ab7d425/TCA-13-2257-g001.jpg

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