Cheng Jun, Guo Chunfen
Department of Cardiothoracic Surgery, Xiangtan Central Hospital, Xiangtan, 411100, Hunan Province, China.
Department of Pathology, Xiangtan Central Hospital, Xiangtan, 411100, Hunan Province, China.
J Cardiothorac Surg. 2025 Jan 7;20(1):44. doi: 10.1186/s13019-024-03259-9.
Primary pulmonary meningioma is a rare disease. There have been only a little over 50 cases of primary pulmonary meningioma (PPM) reported in previous literature. The pathogenesis of PPM is still unclear. We report a case of PPM cured by thoracoscopic right middle lobe wedge resection and systematically review previously reported cases in previous literature.
A 57-year-old male patient was found to have a nodule in the right middle lobe of about 1.8 cm in diameter on a chest-enhanced CT scan performed more than 7 years ago. A re-examination in 2023 found the subpleural nodule in the right middle lobe had grown larger than before. Considering surgical treatment, the patient underwent a thoracoscopic right middle lobe wedge resection after a thorough examination. The final pathological diagnosis was primary pulmonary meningioma. Regular follow-up CT scans showed no recurrence.
Primary pulmonary meningioma is a rare tumor that occurs in sites similar to lung cancer. Most cases are solitary, presenting as ground-glass nodules (GGO), and can occur in multiple lobes, involving the mediastinum and pleura with multiple nodules. Clinical and radiological diagnoses are often challenging, especially distinguishing from primary lung cancer. Surgery remains the optimal choice for the diagnosis and treatment of PPM. Most cases are benign with a good prognosis, and wedge resection is usually the preferred surgical approach. A small proportion of malignant cases may require lobectomy and adjuvant radiotherapy and chemotherapy due to tumor invasiveness.
原发性肺脑膜瘤是一种罕见疾病。既往文献报道的原发性肺脑膜瘤（PPM）仅有50余例。PPM的发病机制仍不清楚。我们报告1例经胸腔镜右中叶楔形切除术治愈的PPM病例，并对既往文献报道的病例进行系统回顾。
一名57岁男性患者7年多前的胸部增强CT扫描发现右中叶有一个直径约1.8 cm的结节。2023年复查发现右中叶胸膜下结节比之前增大。考虑手术治疗，患者在全面检查后接受了胸腔镜右中叶楔形切除术。最终病理诊断为原发性肺脑膜瘤。定期随访CT扫描显示无复发。
原发性肺脑膜瘤是一种罕见肿瘤，发生部位与肺癌相似。大多数病例为单发，表现为磨玻璃结节（GGO），可发生于多个肺叶，伴有多个结节累及纵隔和胸膜。临床和影像学诊断往往具有挑战性，尤其是与原发性肺癌鉴别。手术仍然是PPM诊断和治疗的最佳选择。大多数病例为良性，预后良好，楔形切除术通常是首选的手术方式。少数恶性病例可能因肿瘤侵袭性而需要肺叶切除术及辅助放化疗。
