Department of Chemistry, Faculty of Science, University of Jiroft, P. O. Box 7867161167, Jiroft, Iran.
Department of Pharmaceutics, School of Pharmacy and Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Anal Methods. 2022 Jul 7;14(26):2623-2630. doi: 10.1039/d2ay00426g.
In this study, a three-dimensional adsorbent was developed based on graphene oxide/AgO nanoparticles over interconnected nickel foam (GO/AgO@Ni foam) for rapid and efficient vortex assisted floating solid phase extraction of bisphenol A in canned food products prior to high performance liquid chromatography with a fluorescence detector. The analytical techniques scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and Fourier transform infrared (FT-IR) were used for characterization of the synthetized GO/AgO@Ni foam. The effect of proficiency factors including pH, foam size, vortexing time, salt addition, sample volume, desorption type and volume, and desorption time on the extraction efficiency of bisphenol A were explored through the matrix match method. Under the above experimental conditions, the figures of merit of the method were acquired as LODs (S/N = 3) of 0.18-0.84 μg kg, LOQs of 0.61-2.81 μg kg (S/N = 10), linear ranges of 0.5-500 μg kg, and enrichment factors of 235.5-244.9. The inter-day precision values (RSD%, = 7) of 2.5-3.6 and the intra-day precision (%) of (5 days and seven replicates for each day) 2.8-3.8 were achieved for bisphenol A at a concentration of 50 μg kg. The relative recoveries of 94.0% to 99.6% were obtained for the canned food samples.
在这项研究中，基于氧化石墨烯/氧化银纳米粒子负载在相互连接的泡沫镍上（GO/AgO@Ni 泡沫）开发了一种三维吸附剂，用于在高效液相色谱-荧光检测之前，对罐头食品中的双酚 A 进行快速、高效的涡旋辅助固相反相萃取。扫描电子显微镜（SEM）、能谱（EDX）和傅里叶变换红外（FT-IR）等分析技术用于表征合成的 GO/AgO@Ni 泡沫。通过矩阵匹配法，探讨了影响因素（pH 值、泡沫大小、涡旋时间、盐添加量、样品体积、解吸类型和体积、解吸时间）对双酚 A 萃取效率的影响。在上述实验条件下，获得了该方法的一些优点，包括检出限（S/N = 3）为 0.18-0.84 μg kg、定量限（S/N = 10）为 0.61-2.81 μg kg、线性范围为 0.5-500 μg kg 和富集因子为 235.5-244.9。当双酚 A 的浓度为 50 μg kg 时，日内精密度（RSD%，n = 7）为 2.5-3.6，日间精密度（n = 5 天，每天 7 个重复）为 2.8-3.8。对于罐头食品样品，相对回收率为 94.0%-99.6%。
