Middeldorp C M, Akingbuwa W A, Jami E S, Bartels M
Tijdschr Psychiatr. 2022;64(5):295-300.
Childhood mental health problems are partly influence by genetic factors with heritability estimates varying between 40% and 90%.
We provide examples of genetic research focusing on explaining the continuity of symptoms and the association between parental traits and offspring psychopathology.
We summarize two recently publish review papers RESULTS: There are significant genetic correlations between childhood and adult mental disorders. Genetic factors also explain part of the associations between parental traits and offspring psychopathology, because parents and children share 50% of their genetic material.
The role of genetic factors is not restricted to influencing the risk to develop a mental disorder. They also play a role in persistence of symptoms and the associations with the environment.
儿童心理健康问题部分受遗传因素影响，遗传度估计在40%至90%之间。
我们提供遗传研究的实例，重点解释症状的连续性以及父母特质与后代精神病理学之间的关联。
我们总结了两篇最近发表的综述论文。结果：儿童期和成人期精神障碍之间存在显著的遗传相关性。遗传因素也解释了父母特质与后代精神病理学之间部分关联，因为父母与子女共享50%的遗传物质。
遗传因素的作用不仅限于影响患精神障碍的风险。它们在症状的持续以及与环境的关联中也发挥作用。
