Wu Tao
Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo náměstí 2, 16610, Prague, Czech Republic.
Phys Chem Chem Phys. 2022 Jul 6;24(26):15672-15686. doi: 10.1039/d2cp01641a.
Recently, many studies have appeared in which the Raman optical activity (ROA) instrument was found to be convenient for measuring circularly polarized luminescence (CPL). Typically, weak lanthanide luminescence including circular polarization could be detected. The new detection scheme is referred to as ROA-CPL spectroscopy. It is particularly useful when also the vibrational (ROA) itself is detectable as the molecule structure can be examined more reliably. In this review, development of this chiroptical approach and its applications in structural studies of biomolecules are summarized.
最近，出现了许多研究，其中发现拉曼光学活性（ROA）仪器便于测量圆偏振发光（CPL）。通常，可以检测到包括圆偏振在内的弱镧系元素发光。这种新的检测方案被称为ROA-CPL光谱学。当振动（ROA）本身也可检测到时，它特别有用，因为可以更可靠地检查分子结构。在这篇综述中，总结了这种手性光学方法的发展及其在生物分子结构研究中的应用。
