Department of Biochemistry, All India Institute of Medical Sciences (AIIMS)-Deoghar, Deoghar, Jharkhand, India.
Department of Biotechnology, Periyar University, PG Extension centre, Dharmapuri, Tamilnadu, India.
J Food Biochem. 2022 Oct;46(10):e14282. doi: 10.1111/jfbc.14282. Epub 2022 Jun 23.
In recent years, the application of phytochemicals to prevent or treat diseases has received greater attention. These phytochemicals have little or no toxicity against healthy tissues and are thus considered as ideal compounds. An impressive number of modern drugs are obtained from natural sources based on their traditional value. D-Pinitol is a natural compound that is derived from soy and soy products. It is a potentially active molecule that belongs to the class of inositols. D-pinitol has been pharmacologically evaluated for its potent antioxidant, anti-diabetic, anti-inflammatory, anti-cancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, immunosuppressive, and anti-osteoporotic efficacies. This review is an attempt to validate the plausible pharmacological effects of D-pinitol using various in vivo and in vitro studies. PRACTICAL IMPLICATIONS: The consumption of plant-based products has been significantly increased all over the world. The active phytochemicals that are found in plants are stated to have numerous health promoting functions for the treatment of diabetes, cancer, inflammation, cardiac diseases, liver dysfunction, and many other. D-Pinitol is abundantly present in soybeans that possess notable therapeutic activities. Understanding the effects of D-Pinitol would potentially help in applying this compound in clinical research for the treatment of different disorders.
近年来，植物化学物质在预防和治疗疾病方面的应用受到了更多的关注。这些植物化学物质对健康组织几乎没有毒性，因此被认为是理想的化合物。许多现代药物都是基于其传统价值从天然来源中获得的。D-松醇是一种天然化合物，来源于大豆及其制品。它是一种具有潜在活性的物质，属于肌醇类。D-松醇已在药理学上进行了评估，具有很强的抗氧化、抗糖尿病、抗炎、抗癌、保肝、心脏保护、肾脏保护、神经保护、免疫抑制和抗骨质疏松作用。本综述试图通过各种体内和体外研究来验证 D-松醇合理的药理学作用。实际意义：世界各地植物性产品的消费显著增加。植物中发现的活性植物化学物质据称具有多种促进健康的功能，可用于治疗糖尿病、癌症、炎症、心脏病、肝功能障碍等。D-松醇在大豆中含量丰富，具有显著的治疗活性。了解 D-松醇的作用可能有助于将该化合物应用于临床研究，以治疗不同的疾病。
