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皮下注射肉毒毒素 A 治疗复杂性区域疼痛综合征的难治性疼痛和残疾：病例报告。

Subcutaneous BoNT/A Injection for Intractable Pain and Disability in Complex Regional Pain Syndrome: A Case Report.

机构信息

Clinical Neurology Unit, Udine University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.

Neurology Unit, Udine University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.

出版信息

Toxins (Basel). 2022 Jun 16;14(6):411. doi: 10.3390/toxins14060411.

DOI:10.3390/toxins14060411
PMID:35737072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9227913/
Abstract

We treated a 51-year-old woman with refractory Complex Regional Pain Syndrome type I (CRPS-I) involving her left hand and forearm with subcutaneous injections of BoNT/A. The injections were performed every 3 months, with a total of six treatments. Each treatment was able to effectively improve pain and motor impairment; however, the duration of the effect was limited to only a few months. BoNT/A could improve patients' quality of life with CRPS; however, extensive clinical studies are needed to determine its role in clinical practice.

摘要

我们采用肉毒毒素 A（BoNT/A）皮下注射的方法治疗了一位 51 岁患有左侧手和前臂顽固性复杂性区域疼痛综合征 I 型（CRPS-I）的女性患者。每 3 个月进行一次注射，总共进行了 6 次治疗。每次治疗都能有效改善疼痛和运动障碍；然而，效果的持续时间仅为数月。BoNT/A 可以改善 CRPS 患者的生活质量；然而，还需要广泛的临床研究来确定其在临床实践中的作用。

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