Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.
Centre for Implementation Science, Health Services, Population and Research Department, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.
Soc Psychiatry Psychiatr Epidemiol. 2022 Dec;57(12):2511-2521. doi: 10.1007/s00127-022-02305-y. Epub 2022 Jun 23.
The COVID-19 pandemic may have exacerbated ethnic health inequalities, particularly in people with multiple long-term health conditions, the interplay with mental health is unclear. This study investigates the impact of the pandemic on the association of ethnicity and multimorbidity with mortality/service use among adults, in people living with severe mental illnesses (SMI).
This study will utilise secondary mental healthcare records via the Clinical Record Interactive Search (CRIS) and nationally representative primary care records through the Clinical Practice Interactive Research Database (CPRD). Quasi-experimental designs will be employed to quantify the impact of COVID-19 on mental health service use and excess mortality by ethnicity, in people living with severe mental health conditions. Up to 50 qualitative interviews will also be conducted, co-produced with peer researchers; findings will be synthesised with quantitative insights to provide in-depth understanding of observed associations.
81,483 people in CRIS with schizophrenia spectrum, bipolar or affective disorder diagnoses, were alive from 1st January 2019. Psychiatric multimorbidities in the CRIS sample were comorbid somatoform disorders (30%), substance use disorders (14%) and personality disorders (12%). In CPRD, of 678,842 individuals with a prior probable diagnosis of COVID-19, 1.1% (N = 7493) had an SMI diagnosis. People in the SMI group were more likely to die (9% versus 2% in the non-SMI sample) and were more likely to have mental and physical multimorbidities.
The effect of COVID-19 on people from minority ethnic backgrounds with SMI and multimorbidities remains under-studied. The present mixed methods study aims to address this gap.
COVID-19 大流行可能加剧了种族健康不平等,尤其是在患有多种长期健康状况的人群中,其与心理健康的相互作用尚不清楚。本研究调查了大流行对严重精神疾病(SMI)患者中种族和多种合并症与死亡率/服务使用之间关联的影响。
本研究将利用通过临床记录互动搜索(CRIS)获得的二级精神保健记录和通过临床实践互动研究数据库(CPRD)获得的全国代表性初级保健记录。将采用准实验设计来量化 COVID-19 对严重精神健康状况患者的种族和精神卫生服务使用和超额死亡率的影响。还将进行多达 50 次的定性访谈,由同行研究人员共同进行;研究结果将与定量见解相结合,以深入了解观察到的关联。
CRIS 中有 81483 名患有精神分裂症谱系、双相情感障碍或情感障碍诊断的患者从 2019 年 1 月 1 日起仍然存活。CRIS 样本中的精神共病为躯体形式障碍(30%)、物质使用障碍(14%)和人格障碍(12%)。在 CPRD 中,在 678842 名有先前 COVID-19 可能诊断的个体中,有 1.1%(N=7493)患有 SMI 诊断。SMI 组的人更有可能死亡(9%比非 SMI 组的 2%),并且更有可能患有精神和身体的多种合并症。
COVID-19 对患有 SMI 和多种合并症的少数族裔背景的人的影响仍未得到充分研究。本研究旨在解决这一差距。