• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

2006-2017 年英国综合医院严重精神疾病的诊断:一项登记关联研究。

Severe mental illness diagnosis in English general hospitals 2006-2017: A registry linkage study.

机构信息

Division of Psychiatry, University College London, United Kingdom.

King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom.

出版信息

PLoS Med. 2020 Sep 17;17(9):e1003306. doi: 10.1371/journal.pmed.1003306. eCollection 2020 Sep.

DOI:10.1371/journal.pmed.1003306
PMID:32941435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7498001/
Abstract

BACKGROUND

The higher mortality rates in people with severe mental illness (SMI) may be partly due to inadequate integration of physical and mental healthcare. Accurate recording of SMI during hospital admissions has the potential to facilitate integrated care including tailoring of treatment to account for comorbidities. We therefore aimed to investigate the sensitivity of SMI recording within general hospitals, changes in diagnostic accuracy over time, and factors associated with accurate recording.

METHODS AND FINDINGS

We undertook a cohort study of 13,786 adults with SMI diagnosed during 2006-2017, using data from a large secondary mental healthcare database as reference standard, linked to English national records for 45,706 emergency hospital admissions. We examined general hospital record sensitivity across patients' subsequent hospital records, for each subsequent emergency admission, and at different levels of diagnostic precision. We analyzed time trends during the study period and used logistic regression to examine sociodemographic and clinical factors associated with psychiatric recording accuracy, with multiple imputation for missing data. Sensitivity for recording of SMI as any mental health diagnosis was 76.7% (95% CI 76.0-77.4). Category-level sensitivity (e.g., proportion of individuals with schizophrenia spectrum disorders (F20-29) who received any F20-29 diagnosis in hospital records) was 56.4% (95% CI 55.4-57.4) for schizophrenia spectrum disorder and 49.7% (95% CI 48.1-51.3) for bipolar affective disorder. Sensitivity for SMI recording in emergency admissions increased from 47.8% (95% CI 43.1-52.5) in 2006 to 75.4% (95% CI 68.3-81.4) in 2017 (ptrend < 0.001). Minority ethnicity, being married, and having better mental and physical health were associated with less accurate diagnostic recording. The main limitation of our study is the potential for misclassification of diagnosis in the reference-standard mental healthcare data.

CONCLUSIONS

Our findings suggest that there have been improvements in recording of SMI diagnoses, but concerning under-recording, especially in minority ethnic groups, persists. Training in culturally sensitive diagnosis, expansion of liaison psychiatry input in general hospitals, and improved data sharing between physical and mental health services may be required to reduce inequalities in diagnostic practice.

摘要

背景

严重精神疾病(SMI)患者的死亡率较高,部分原因可能是身心保健整合不足。在住院期间准确记录 SMI 有潜力促进综合护理,包括针对合并症调整治疗。因此,我们旨在调查综合医院中 SMI 记录的敏感性、随时间变化的诊断准确性变化,以及与准确记录相关的因素。

方法和发现

我们对 2006 年至 2017 年间确诊的 13786 名 SMI 成年患者进行了队列研究,使用来自大型二级精神卫生保健数据库的数据作为参考标准,与英格兰全国 45706 例紧急住院记录相链接。我们检查了患者随后的住院记录、每次随后的紧急入院记录以及不同诊断精度水平下综合医院记录的敏感性。我们分析了研究期间的时间趋势,并使用逻辑回归分析了与精神科记录准确性相关的社会人口学和临床因素,对缺失数据进行了多重插补。记录任何心理健康诊断的 SMI 的敏感性为 76.7%(95%CI 76.0-77.4)。类别水平敏感性(例如,精神分裂症谱系障碍(F20-29)患者中有多少人在医院记录中接受了任何 F20-29 诊断),精神分裂症谱系障碍为 56.4%(95%CI 55.4-57.4),双相情感障碍为 49.7%(95%CI 48.1-51.3)。2006 年急诊入院 SMI 记录的敏感性为 47.8%(95%CI 43.1-52.5),2017 年为 75.4%(95%CI 68.3-81.4)(ptrend <0.001)。少数民族、已婚和更好的精神和身体健康与不太准确的诊断记录相关。我们研究的主要限制是参考标准精神保健数据中诊断可能存在分类错误。

结论

我们的研究结果表明,在记录 SMI 诊断方面有所改善,但令人担忧的是,尤其是在少数民族群体中,记录不足的情况仍然存在。可能需要进行文化敏感诊断培训、扩大综合医院联络精神病学投入以及改善身心健康服务之间的数据共享,以减少诊断实践中的不平等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2dd/7498001/daddf93e99c4/pmed.1003306.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2dd/7498001/63f08e300099/pmed.1003306.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2dd/7498001/daddf93e99c4/pmed.1003306.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2dd/7498001/63f08e300099/pmed.1003306.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2dd/7498001/daddf93e99c4/pmed.1003306.g002.jpg

相似文献

1
Severe mental illness diagnosis in English general hospitals 2006-2017: A registry linkage study.2006-2017 年英国综合医院严重精神疾病的诊断:一项登记关联研究。
PLoS Med. 2020 Sep 17;17(9):e1003306. doi: 10.1371/journal.pmed.1003306. eCollection 2020 Sep.
2
The incidence rate of planned and emergency physical health hospital admissions in people diagnosed with severe mental illness: a cohort study.诊断患有严重精神疾病的人群中计划性和紧急性身体健康住院治疗的发生率:一项队列研究。
Psychol Med. 2023 Sep;53(12):5603-5614. doi: 10.1017/S0033291722002811. Epub 2022 Sep 7.
3
Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study.85979 例严重精神疾病患者的医院谵妄诊断发生率及相关性:一项数据链接研究。
Acta Psychiatr Scand. 2023 May;147(5):516-526. doi: 10.1111/acps.13480. Epub 2022 Aug 5.
4
The development of type 2 diabetes management in people with severe mental illness in the Capital Region of Denmark from 2001 to 2015.丹麦首都大区 2001 至 2015 年期间严重精神疾病患者 2 型糖尿病管理的发展。
Acta Psychiatr Scand. 2024 Mar;149(3):219-233. doi: 10.1111/acps.13650. Epub 2024 Jan 6.
5
Ethnicity and cardiovascular health inequalities in people with severe mental illnesses: protocol for the E-CHASM study.严重精神疾病患者的种族与心血管健康不平等:E-CHASM研究方案
Soc Psychiatry Psychiatr Epidemiol. 2016 Apr;51(4):627-38. doi: 10.1007/s00127-016-1185-8. Epub 2016 Feb 4.
6
Clustering of physical health multimorbidity in people with severe mental illness: An accumulated prevalence analysis of United Kingdom primary care data.精神疾病患者躯体健康多种共病的聚类:英国初级保健数据的累积患病率分析。
PLoS Med. 2022 Apr 20;19(4):e1003976. doi: 10.1371/journal.pmed.1003976. eCollection 2022 Apr.
7
Recording of severe mental illness in United Kingdom primary care, 2000-2010.英国初级医疗保健中严重精神疾病的记录,2000-2010 年。
PLoS One. 2013 Dec 12;8(12):e82365. doi: 10.1371/journal.pone.0082365. eCollection 2013.
8
Cardiovascular disease treatment among patients with severe mental illness: a data linkage study between primary and secondary care.重度精神疾病患者的心血管疾病治疗:一项初级和二级医疗之间的数据关联研究
Br J Gen Pract. 2016 Jun;66(647):e374-81. doi: 10.3399/bjgp16X685189. Epub 2016 Apr 25.
9
Do care plans and annual reviews of physical health influence unplanned hospital utilisation for people with serious mental illness? Analysis of linked longitudinal primary and secondary healthcare records in England.护理计划和身体健康年度评估对严重精神疾病患者的非计划住院使用情况有影响吗?对英格兰纵向关联的初级和二级医疗保健记录的分析。
BMJ Open. 2018 Nov 28;8(11):e023135. doi: 10.1136/bmjopen-2018-023135.
10
Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK.躯体共病的不平等:英国严重精神疾病患者的纵向比较队列研究
BMJ Open. 2015 Dec 15;5(12):e009010. doi: 10.1136/bmjopen-2015-009010.

引用本文的文献

1
Racial bias in clinician assessment of patient credibility: Evidence from electronic health records.临床医生对患者可信度评估中的种族偏见:来自电子健康记录的证据。
PLoS One. 2025 Aug 13;20(8):e0328134. doi: 10.1371/journal.pone.0328134. eCollection 2025.
2
Antipsychotic management in general practice: serial cross-sectional study (2011-2020).全科医疗中的抗精神病药物管理:系列横断面研究(2011 - 2020年)
Br J Gen Pract. 2024 Dec 26;75(750):e68-e79. doi: 10.3399/BJGP.2024.0367. Print 2025 Jan.
3
Recording of intellectual disability in general hospitals in England 2006-2019: Cohort study using linked datasets.

本文引用的文献

1
The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness.《柳叶刀》精神病学委员会:保护精神疾病患者身体健康的蓝图。
Lancet Psychiatry. 2019 Aug;6(8):675-712. doi: 10.1016/S2215-0366(19)30132-4. Epub 2019 Jul 16.
2
Heterogeneity in psychiatric diagnostic classification.精神疾病诊断分类的异质性。
Psychiatry Res. 2019 Sep;279:15-22. doi: 10.1016/j.psychres.2019.07.005. Epub 2019 Jul 2.
3
Continuity of care and clinical outcomes in the community for people with severe mental illness.
2006-2019 年英格兰综合医院智障记录:使用关联数据集的队列研究。
PLoS Med. 2023 Mar 20;20(3):e1004117. doi: 10.1371/journal.pmed.1004117. eCollection 2023 Mar.
4
Ethnic inequities in multimorbidity among people with psychosis: a retrospective cohort study.精神分裂症患者多种共病的种族不平等:一项回顾性队列研究。
Epidemiol Psychiatr Sci. 2022 Jul 18;31:e52. doi: 10.1017/S2045796022000385.
5
Patient-centric characterization of multimorbidity trajectories in patients with severe mental illnesses: A temporal bipartite network modeling approach.以患者为中心的严重精神疾病患者多种共病轨迹特征:一种时间二分网络建模方法。
J Biomed Inform. 2022 Mar;127:104010. doi: 10.1016/j.jbi.2022.104010. Epub 2022 Feb 11.
6
Psychiatric disorders among hospitalized patients deceased with COVID-19 in Italy.意大利因新冠肺炎死亡的住院患者中的精神障碍情况。
EClinicalMedicine. 2021 May;35:100854. doi: 10.1016/j.eclinm.2021.100854. Epub 2021 Apr 23.
严重精神疾病患者在社区中的连续护理和临床结局。
Br J Psychiatry. 2019 May;214(5):273-278. doi: 10.1192/bjp.2018.261.
4
Ethnic variations in compulsory detention under the Mental Health Act: a systematic review and meta-analysis of international data.《精神卫生法》规定下强制拘留中的种族差异:对国际数据的系统评价与荟萃分析
Lancet Psychiatry. 2019 Apr;6(4):305-317. doi: 10.1016/S2215-0366(19)30027-6. Epub 2019 Mar 4.
5
Accuracy of general hospital dementia diagnoses in England: Sensitivity, specificity, and predictors of diagnostic accuracy 2008-2016.2008-2016 年英国综合医院痴呆诊断的准确性:敏感性、特异性和诊断准确性的预测因素。
Alzheimers Dement. 2018 Jul;14(7):933-943. doi: 10.1016/j.jalz.2018.02.012. Epub 2018 Apr 25.
6
Experiencing mental health diagnosis: a systematic review of service user, clinician, and carer perspectives across clinical settings.经历心理健康诊断:对临床环境中服务使用者、临床医生和护理人员观点的系统评价
Lancet Psychiatry. 2018 Sep;5(9):747-764. doi: 10.1016/S2215-0366(18)30095-6. Epub 2018 Apr 18.
7
Using data linkage to electronic patient records to assess the validity of selected mental health diagnoses in English Hospital Episode Statistics (HES).利用电子患者记录的数据链接来评估英国医院入院统计(HES)中选定精神健康诊断的有效性。
PLoS One. 2018 Mar 26;13(3):e0195002. doi: 10.1371/journal.pone.0195002. eCollection 2018.
8
Acute general hospital admissions in people with serious mental illness.严重精神疾病患者的急性综合医院入院情况。
Psychol Med. 2018 Dec;48(16):2676-2683. doi: 10.1017/S0033291718000284. Epub 2018 Feb 28.
9
Polypharmacy in people with dementia: Associations with adverse health outcomes.痴呆患者的多种药物治疗:与不良健康结局的关联。
Exp Gerontol. 2018 Jun;106:240-245. doi: 10.1016/j.exger.2018.02.011. Epub 2018 Feb 13.
10
Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000-2014.双相情感障碍和精神分裂症患者的死亡率差距:英国基于队列的研究 2000-2014 年。
Br J Psychiatry. 2017 Sep;211(3):175-181. doi: 10.1192/bjp.bp.117.202606. Epub 2017 Jul 6.