美国新墨西哥州沙漠棉尾兔（Sylvilagus audubonii）中新发复发性回归热螺旋体种的分子特征。
Molecular Characterization of a Novel Relapsing Fever Borrelia Species from the Desert Cottontail (Sylvilagus audubonii) in New Mexico, USA.
机构信息
Centers for Disease Control and Prevention, 3156 Rampart Road, Fort Collins, Colorado 80521, USA.
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, Maryland 21205, USA.
出版信息
J Wildl Dis. 2022 Jul 1;58(3):646-651. doi: 10.7589/JWD-D-21-00148.
The Borrelia genus comprises vector-borne, spirochete bacteria infecting vertebrates worldwide. We characterized a novel relapsing fever Borrelia species from a desert cottontail (Syvilagus audubonii) from New Mexico, US, using an established multilocus sequence analysis approach. Phylogenetic analysis of the flagellin gene (flaB) and four other protein-coding loci (clpX, pepX, recG, rplB) grouped the novel Borrelia species with hard tick relapsing fever borreliae Borrelia lonestari, Borrelia theileri, and Borrelia miyamotoi. The identity of the vectors and other vertebrate hosts, geographic distribution, and zoonotic potential of this novel Borrelia species deserve further investigation.
该螺旋体属包括通过媒介传播的、感染全世界脊椎动物的螺旋体细菌。我们采用已建立的多位点序列分析方法，从美国新墨西哥州的沙漠棉尾兔（Syvilagus audubonii）中鉴定出一种新型回归热螺旋体物种。鞭毛蛋白基因（flaB）和其他四个蛋白编码基因座（clpX、pepX、recG、rplB）的系统发育分析将新型 Borrelia 物种与硬蜱回归热螺旋体 Borrelia lonestari、Borrelia theileri 和 Borrelia miyamotoi 分组在一起。这种新型 Borrelia 物种的媒介和其他脊椎动物宿主、地理分布和人畜共患病潜力值得进一步研究。
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