Early Bacterial Virulence: Borrelia Group, Université de Strasbourg, Facultés de Médecine et de Pharmacie, CHRU Strasbourg, Fédération de Médecine Translationnelle de Strasbourg, VBB EA 7290, Strasbourg, France.
Department of Molecular Biology, Umeå University, Umeå, Sweden.
Front Cell Infect Microbiol. 2018 Apr 4;8:98. doi: 10.3389/fcimb.2018.00098. eCollection 2018.
Relapsing fever still remains a neglected disease and little is known on its reservoir, tick vector and physiopathology in the vertebrate host. The disease occurs in temperate as well as tropical countries. Relapsing fever borreliae are spirochaetes, members of the family which also contain Lyme disease spirochaetes. They are mainly transmitted by soft ticks, but some species are vectored by ixodid ticks. Traditionally a species is associated with a specific vector in a particular geographical area. However, new species are regularly described, and taxonomical uncertainties deserve further investigations to better understand vector/host adaptation. The medical importance of , transmitted by spp., has recently spawned new interest in this bacterial group. In this review, recent data on tick-host-pathogen interactions for tick-borne relapsing fevers is presented, with special focus on .
回归热仍然是一种被忽视的疾病，人们对其在脊椎动物宿主中的储存宿主、蜱媒介和病理生理学知之甚少。这种疾病发生在温带和热带国家。回归热螺旋体是螺旋体，属于包含莱姆病螺旋体的家族。它们主要通过软蜱传播，但有些物种由硬蜱传播。传统上，一种物种与特定地理区域的特定媒介相关联。然而，新物种经常被描述，分类学上的不确定性需要进一步研究，以更好地了解媒介/宿主的适应。由 spp.传播的 的医学重要性最近引起了人们对这组细菌的新兴趣。在这篇综述中，介绍了有关蜱传回归热的蜱-宿主-病原体相互作用的最新数据，特别关注 。
