Ilik Yerel, IJsselstijn Hanneke, Gischler Saskia J, van Gils-Frijters Annabel, Schnater Johannes M, Rietman Andre B
Department of Pediatric Surgery and Intensive Care, Erasmus MC Sophia Children's Hospital, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC Sophia Children's Hospital, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Children (Basel). 2022 Jun 16;9(6):900. doi: 10.3390/children9060900.
Children with congenital anatomical foregut anomalies and children treated with neonatal extracorporeal membrane oxygenation (ECMO) are at risk for neurocognitive morbidities. We evaluated the association between the parent-reported pediatric perceived cognitive functioning (PedsPCF) questionnaire and the parent-reported behavior rating inventory of executive function (BRIEF) as well as neuropsychological assessments (NPA). We included 8-, 12- and 17-year-old participants who had joined a prospective follow-up program between 2017 and 2019. Self- and parental proxy-reported PedsPCF and proxy-reported BRIEF scores and their mutual association were evaluated. In total, 168 participants were included. Self- and proxy-reported PedsPCF scores were significantly below normal (mean (SD) z-score: −0.35 (0.88), p < 0.001; −0.36 (1.06), p < 0.001, respectively). Total BRIEF scores were significantly above normal (mean (SD) z-score 0.33 (0.98), p < 0.001). Proxy-reported PedsPCF scores and the Metacognition Index subscores of the BRIEF correlated strongly (τ = 0.551, p < 0.001). Self-reported PedsPCF scores were not associated with NPA test scores. Proxy-reported PedsPCF scores were positively associated with multiple NPA test scores, especially intelligence (R2 = 0.141). The proxy-reported PedsPCF revealed cognitive problems more often than the BRIEF in school-aged children who had survived neonatal critical illness. The proxy-reported PedsPCF may support clinical decision-making regarding the need for extensive neuropsychological assessments.
患有先天性前肠解剖异常的儿童以及接受新生儿体外膜肺氧合（ECMO）治疗的儿童存在神经认知疾病的风险。我们评估了家长报告的儿童感知认知功能（PedsPCF）问卷与家长报告的执行功能行为评定量表（BRIEF）以及神经心理学评估（NPA）之间的关联。我们纳入了2017年至2019年间参加前瞻性随访项目的8岁、12岁和17岁参与者。评估了自我报告和家长代理报告的PedsPCF、代理报告的BRIEF分数及其相互关联。总共纳入了168名参与者。自我报告和代理报告的PedsPCF分数均显著低于正常水平（平均（标准差）z分数：分别为−0.35（0.88），p<0.001；−0.36（1.06），p<0.001）。BRIEF总分显著高于正常水平（平均（标准差）z分数0.33（0.98），p<0.001）。代理报告的PedsPCF分数与BRIEF的元认知指数子分数密切相关（τ = 0.551，p<0.001）。自我报告的PedsPCF分数与NPA测试分数无关。代理报告的PedsPCF分数与多个NPA测试分数呈正相关，尤其是智力（R2 = 0.141）。在新生儿危重症存活的学龄儿童中，代理报告的PedsPCF比BRIEF更常揭示认知问题。代理报告的PedsPCF可能有助于支持关于是否需要进行广泛神经心理学评估的临床决策。
