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测量MRI中健康和退变腰椎间盘高度及体积的新方法:一项可靠性评估研究。

Novel Methods to Measure Height and Volume in Healthy and Degenerated Lumbar Discs in MRIs: A Reliability Assessment Study.

作者信息

Guellil Nadya, Argawal Neha, Krieghoff Magnus, Kaden Ingmar, Hohaus Christian, Meisel Hans-Joerg, Schenk Philipp

机构信息

Department of Plastic and Hand Surgery, Burn Unit, BG Klinikum Bergmannstrost Halle, 06112 Halle, Germany.

Department of Neurosurgery, BG Klinikum Bergmannstrost Halle, 06112 Halle, Germany.

出版信息

Diagnostics (Basel). 2022 Jun 10;12(6):1437. doi: 10.3390/diagnostics12061437.

DOI:10.3390/diagnostics12061437
PMID:35741247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9221833/
Abstract

BACKGROUND

In the regeneration and therapy of degenerated intervertebral discs, the height, volume or categorizing assessments, such as Pfirrmann classification, are used to quantify the discs themselves and the effects of therapy. Here, the question of transferability, in the sense of reliability, of the results arises in the common exchange.

METHODS

We have investigated two established and a newly developed (9-point measurement), easy to use methods for height measurement and volume measurement on degenerated and healthy lumbar intervertebral discs of 66 patients regarding inter- and intra-observer reliability.

RESULTS

In overview, we found very different reliabilities. While the intra-observer reliability showed good to excellent agreement for both healthy and degenerated lumbar discs for the height and volume measurements, the inter-observer reliability was low or moderate in some cases. The 9-point method for height determination consistently showed better reliability for both healthy and degenerated discs, for both intra- and inter-observer reliability, compared to the two established methods.

CONCLUSIONS

We recommend using the 9-point measurement as the method to communicate lumbar disc height, both for healthy and degenerated discs. Due to the partly low or moderate reliability, significant differences in the measured heights can already occur, which can lead to a worsened comparability.

摘要

背景

在退变椎间盘的再生与治疗中,椎间盘高度、体积或分类评估(如Pfirrmann分级)用于量化椎间盘本身及治疗效果。在此,在常见的交流中会出现结果在可靠性方面的可转移性问题。

方法

我们研究了两种已确立的以及一种新开发的(9分测量法)、易于使用的测量退变和健康腰椎间盘高度及体积的方法,涉及观察者间及观察者内的可靠性,研究对象为66例患者。

结果

总体而言,我们发现可靠性差异很大。虽然观察者内可靠性在健康和退变腰椎间盘的高度及体积测量方面均显示出良好到极佳的一致性,但观察者间可靠性在某些情况下较低或中等。与两种已确立的方法相比,9分法测量高度在健康和退变椎间盘的观察者内及观察者间可靠性方面均始终表现出更好的可靠性。

结论

我们建议使用9分测量法来传达健康和退变椎间盘的腰椎间盘高度。由于部分可靠性较低或中等,测量高度可能已经出现显著差异,这可能导致可比性变差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/b96aab82e8d1/diagnostics-12-01437-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/d2c3e32a0094/diagnostics-12-01437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/ccba9ea75866/diagnostics-12-01437-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/b96aab82e8d1/diagnostics-12-01437-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/d2c3e32a0094/diagnostics-12-01437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/ccba9ea75866/diagnostics-12-01437-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/9221833/b96aab82e8d1/diagnostics-12-01437-g003.jpg

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3
Relationship between size of disc and early postoperative outcomes after lumbar discectomy.
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Arch Orthop Trauma Surg. 2017 Jun;137(6):805-811. doi: 10.1007/s00402-017-2699-6. Epub 2017 Apr 28.
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Autophagy Is a Protective Response to the Oxidative Damage to Endplate Chondrocytes in Intervertebral Disc: Implications for the Treatment of Degenerative Lumbar Disc.自噬是对椎间盘终板软骨细胞氧化损伤的一种保护反应:对退行性腰椎间盘治疗的启示
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