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腰椎间盘切除术后椎间盘大小与早期术后结果的关系。

Relationship between size of disc and early postoperative outcomes after lumbar discectomy.

作者信息

En'Wezoh Derick C, Leonard Dana A, Schoenfeld Andrew J, Harris Mitchel B, Zampini Jay M, Bono Christopher M

机构信息

Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.

Department of Orthopaedic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.

出版信息

Arch Orthop Trauma Surg. 2017 Jun;137(6):805-811. doi: 10.1007/s00402-017-2699-6. Epub 2017 Apr 28.

Abstract

BACKGROUND

Previous studies suggest that patients with larger disc herniations (greater than 6 mm) will have better outcomes following discectomy. This has not been validated in a large series of patients.

PURPOSE

We sought to empirically evaluate this relationship in a series of patients who had data collected prospectively as part of a randomized trial.

METHODS

This retrospective review included 63 consecutive adult patients who underwent a single-level, primary lumbar discectomy. Outcomes were VAS for leg and back pain and the modified oswestry disability index (MODI). Statistical tests were used to compare patients using different cutoffs of preoperative disc diameters and disc volume removed. Regression analysis was performed to determine if there was a relationship between outcomes and the measured parameters.

RESULTS

While patients who achieved substantial clinical benefit (SCB) for MODI had larger disc diameters, this relationship was not found for leg or back pain for any of the measured parameters. Using 5, 6, 7, or 8 mm as a cutoff for disc diameter demonstrated no differences. Regression analysis did not demonstrate a significant relationship between disc volume removed and final MODI scores.

CONCLUSION

While patients with larger disc herniations on average might have a greater likelihood of superior clinical outcomes, the previously suggested "6 mm rule" was not supported.

摘要

背景

先前的研究表明,椎间盘突出较大(大于6毫米)的患者在椎间盘切除术后会有更好的预后。这一点尚未在大量患者中得到验证。

目的

我们试图在前瞻性收集数据作为随机试验一部分的一系列患者中,通过实证评估这种关系。

方法

这项回顾性研究纳入了63例连续接受单节段初次腰椎间盘切除术的成年患者。结局指标为腿部和背部疼痛的视觉模拟评分(VAS)以及改良奥斯维斯特里功能障碍指数(MODI)。使用统计检验比较术前椎间盘直径和切除椎间盘体积的不同临界值的患者。进行回归分析以确定结局与测量参数之间是否存在关系。

结果

虽然在MODI方面获得显著临床益处(SCB)的患者椎间盘直径较大,但在所测量的任何参数中,腿部或背部疼痛方面均未发现这种关系。以5、6、7或8毫米作为椎间盘直径的临界值未显示出差异。回归分析未显示切除椎间盘体积与最终MODI评分之间存在显著关系。

结论

虽然平均而言,椎间盘突出较大的患者可能更有可能获得更好的临床结局,但先前提出的“6毫米规则”未得到支持。

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