Desrochers M, Peloquin L, Săsărman A
J Bacteriol. 1978 Sep;135(3):1151-3. doi: 10.1128/jb.135.3.1151-1153.1978.
A new type of heme-deficient mutant was isolated in Salmonella typhimurium by neomycin selection. The mutant was deficient in uroporphyrinogen decarboxylase activity, coded by the hemE gene. The hemE gene was located between the genes rif and thi at 128 min on the chromosomal map of S. typhimurium.
通过新霉素筛选,在鼠伤寒沙门氏菌中分离出一种新型的血红素缺陷型突变体。该突变体缺乏由hemE基因编码的尿卟啉原脱羧酶活性。hemE基因位于鼠伤寒沙门氏菌染色体图谱上128分钟处的rif和thi基因之间。