Dubart A, Mattei M G, Raich N, Beaupain D, Romeo P H, Mattei J F, Goossens M
Hum Genet. 1986 Jul;73(3):277-9. doi: 10.1007/BF00401245.
A cDNA probe corresponding to mRNA encoding human uroporphyrinogen decarboxylase (URO-D) was used to determine the chromosomal localization of the URO-D gene in the human genome. In agreement with previous studies, we have found that the locus for URO-D is located on chromosome 1 in hybrid cell mapping panels. The use of in situ hybridization allowed us to map the URO-D locus to band 1p34.
使用与编码人尿卟啉原脱羧酶(URO-D)的mRNA对应的cDNA探针来确定URO-D基因在人类基因组中的染色体定位。与先前的研究一致,我们发现在杂交细胞作图板中,URO-D基因座位于1号染色体上。原位杂交技术的应用使我们能够将URO-D基因座定位到1p34带。