Katsarou Martha-Spyridoula, Iasonidou Eleni, Osarogue Alexander, Kalafatis Efthymios, Stefanatou Maria, Pappa Sofia, Gatzonis Stylianos, Verentzioti Anastasia, Gounopoulos Pantelis, Demponeras Christos, Konstantinidou Eleni, Drakoulis Nikolaos, Asimakos Andreas, Antonoglou Archontoula, Mavronasou Aspasia, Spetsioti Stavroula, Kotanidou Anastasia, Katsaounou Paraskevi
Research Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15771 Zografou, Greece.
Long COVID Greece Patient Society, 57010 Thessaloniki, Greece.
J Pers Med. 2022 Jun 17;12(6):987. doi: 10.3390/jpm12060987.
Long COVID-19 syndrome refers to persisting symptoms (>12 weeks) after the initial coronavirus infection and is estimated to affect 3% to 12% of people diagnosed with the disease globally. Aim: We conducted a collaborative study with the Long COVID patient organization in Greece, in order to estimate the characteristics, symptoms, and challenges these patients confront. Methods: Data were collected from 208 patients using unstructured qualitative free-text entries in an anonymized online questionnaire. Results: The majority of respondents (68.8%) were not hospitalized and reported lingering symptoms (66.8%) for more than six months. Eighteen different symptoms (fatigue, palpitations, shortness of breath, parosmia, etc.) were mentioned in both hospitalized and community patients. Awareness of Long COVID sequelae seems to be low even among medical doctors. Treatment options incorporating targeted rehabilitation programs are either not available or still not included inthe management plan of Long COVID patients. Conclusions: Patients infected with coronavirus with initial mild symptoms suffer from the same persistent symptoms as those who were hospitalized. Long COVID syndrome appears to be a multi-systemic entity and a multidisciplinary medical approach should be adopted in order to correctly diagnose and successfully manage these patients.
新冠长期综合征是指初次感染新冠病毒后持续出现的症状（超过12周），据估计全球3%至12%的新冠确诊患者会受到影响。目的：我们与希腊的新冠长期患者组织开展了一项合作研究，以评估这些患者的特征、症状及面临的挑战。方法：通过一份匿名在线问卷中无结构定性自由文本条目，从208名患者处收集数据。结果：大多数受访者（68.8%）未住院，且报告有持续超过六个月的症状（66.8%）。住院患者和社区患者都提到了18种不同症状（疲劳、心悸、呼吸急促、嗅觉异常等）。即使在医生中，对新冠长期后遗症的认知似乎也较低。包含针对性康复计划的治疗方案要么不可用，要么仍未纳入新冠长期患者的管理计划。结论：最初症状较轻的新冠感染患者与住院患者有相同的持续症状。新冠长期综合征似乎是一种多系统疾病，应采用多学科医疗方法来正确诊断和成功管理这些患者。
