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基于电偶合的传导性心内通信的可变容积心脏模型。

A Variable-Volume Heart Model for Galvanic Coupling-Based Conductive Intracardiac Communication.

机构信息

College of Physics and Information Engineering, Fuzhou University, Fuzhou 350108, China.

State Key Laboratory of Analog and Mixed-Signal VLSL, University of Macau, Macao, China.

出版信息

Sensors (Basel). 2022 Jun 12;22(12):4455. doi: 10.3390/s22124455.

DOI:10.3390/s22124455
PMID:35746237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9228749/
Abstract

Conductive intracardiac communication (CIC) has become one of the most promising technologies in multisite leadless pacemakers for cardiac resynchronization therapy. Existing studies have shown that cardiac pulsation has a significant impact on the attenuation of intracardiac communication channels. In this study, a novel variable-volume circuit-coupled electrical field heart model, which contains blood and myocardium, is proposed to verify the phenomenon. The influence of measurements was combined with the model as the equivalent circuit. Dynamic intracardiac channel characteristics were obtained by simulating models with varying volumes of the four chambers according to the actual cardiac cycle. Subsequently, in vitro experiments were carried out to verify the model's correctness. Among the dependences of intracardiac communication channels, the distance between pacemakers exerted the most substantial influence on attenuation. In the simulation and measurement, the relationship between channel attenuation and pulsation was found through the variable-volume heart model and a porcine heart. The CIC channel attenuation had a variation of less than 3 dB.

摘要

心内传导(CIC)已成为多部位无导线起搏器心脏再同步治疗中最有前途的技术之一。现有研究表明,心脏搏动对心内通讯通道的衰减有显著影响。本研究提出了一种新型的可变容积电路耦合电场心脏模型,用于验证该现象。将测量的影响与模型结合作为等效电路。根据实际心动周期,模拟四个腔室容积变化的模型,获得动态心内通道特性。随后,进行了离体实验以验证模型的正确性。在心内通讯通道的依赖关系中,起搏器之间的距离对衰减的影响最大。在模拟和测量中,通过可变容积心脏模型和猪心发现了通道衰减与搏动之间的关系。CIC 通道衰减的变化小于 3dB。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f2/9228749/4eebb7d5be9a/sensors-22-04455-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f2/9228749/d294bc6dd61c/sensors-22-04455-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96f2/9228749/06d01e9d0bd9/sensors-22-04455-g009.jpg
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本文引用的文献

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Wide Frequency Characterization of Intra-Body Communication for Leadless Pacemakers.用于无导线起搏器的体内通信的宽频特性分析
IEEE Trans Biomed Eng. 2020 Nov;67(11):3223-3233. doi: 10.1109/TBME.2020.2980205. Epub 2020 Mar 12.
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Leadless cardiac resynchronization therapy: An in vivo proof-of-concept study of wireless pacemaker synchronization.无导线心脏再同步治疗:无线起搏器同步的体内概念验证研究。
Heart Rhythm. 2019 Jun;16(6):936-942. doi: 10.1016/j.hrthm.2019.01.010. Epub 2019 Jan 11.
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用于无导线多部位起搏器系统的导电心内通信的基本特性描述。
IEEE Trans Biomed Circuits Syst. 2019 Feb;13(1):237-247. doi: 10.1109/TBCAS.2018.2886042. Epub 2018 Dec 10.
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