Ferraro Giuseppe A, Lanzano Giuseppe, Grella Elisa, Gubitosi Adelmo, Nicoletti Giovanni F
Plastic and Reconstructive Surgery Unit, Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy.
Plast Reconstr Surg Glob Open. 2022 Jun 20;10(6):e4360. doi: 10.1097/GOX.0000000000004360. eCollection 2022 Jun.
The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it is well known that postbariatric patients present aberrant wound healing due to multifactorial causes, such as preoperative illness, nutritional deficiencies, and vascular disease. To treat such complex wounds, several methods have been recommended, such as the use of negative pressure wound therapy, tissue-engineered skin substitutes, and collagen-based wound dressings. The case presented here is of a patient with deep wound dehiscence of the inner left thigh, 1 week after a medial thigh lift procedure, successfully managed with Vergenix Flowable Gel, a human recombinant type I collagen produced in plants. After 2 weeks of treatment, wound dehiscence was replaced with granulation tissue, and after 4 weeks, the patient was completely healed, with an acceptable aesthetic outcome of the surgical scar.
减肥后对身体塑形手术的需求不断增加,与此同时伤口并发症也在增多。因此,手术再次干预或保守治疗是必要的,这对医疗保健专业人员来说是一项艰巨的挑战。此外,众所周知,减肥后的患者由于多种因素,如术前疾病、营养缺乏和血管疾病,会出现伤口愈合异常。为了治疗这类复杂伤口,人们推荐了几种方法,如使用负压伤口疗法、组织工程皮肤替代品和基于胶原蛋白的伤口敷料。这里介绍的病例是一名患者,在内侧大腿提升手术后1周,左大腿内侧出现深部伤口裂开,使用在植物中生产的人重组I型胶原蛋白Vergenix Flowable Gel成功治疗。经过2周的治疗,伤口裂开处被肉芽组织取代,4周后患者完全愈合,手术疤痕的美学效果可接受。