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大鼠视网膜各层中天冬氨酸转氨酶同工酶活性的分布。

Distributions of the activities of aspartate aminotransferase isoenzymes in rat retinal layers.

作者信息

Ross C D, Bowers M, Godfrey D A

出版信息

Neurosci Lett. 1987 Feb 24;74(2):205-10. doi: 10.1016/0304-3940(87)90150-9.

DOI:10.1016/0304-3940(87)90150-9
PMID:3574759
Abstract

Distributions of the activities of the cytosolic (cAAT) and mitochondrial (mAAT) isoenzymes of aspartate aminotransferase were determined in rat retinal layers. cAAT was highest in the photoreceptor inner segments, inner nuclear layer and inner plexiform layer; mAAT was highest in the inner segments. The high activity in the inner segments indicates that both isoenzymes are involved in energy metabolism in addition to a possible role in neurotransmission.

摘要

测定了大鼠视网膜各层中天冬氨酸氨基转移酶的胞质(cAAT)和线粒体(mAAT)同工酶的活性分布。cAAT在光感受器内段、内核层和内网状层中活性最高;mAAT在内段中活性最高。内段中的高活性表明这两种同工酶除了在神经传递中可能发挥作用外,还参与能量代谢。

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2
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Precursors of glutamic acid nitrogen in primary neuronal cultures: studies with 15N.
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Neurochem Res. 1990 Dec;15(12):1191-6. doi: 10.1007/BF01208579.