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投射至猫腰骶部和颈部脊髓的5-羟色胺能和非5-羟色胺能中缝神经元:一项定量辣根过氧化物酶免疫细胞化学研究

Serotonergic and non-serotonergic raphe neurons projecting to the feline lumbar and cervical spinal cord: a quantitative horseradish peroxidase-immunocytochemical study.

作者信息

Bowker R M, Reddy V K, Fung S J, Chan J Y, Barnes C D

出版信息

Neurosci Lett. 1987 Mar 20;75(1):31-7. doi: 10.1016/0304-3940(87)90070-x.

DOI:10.1016/0304-3940(87)90070-x
PMID:3574767
Abstract

A quantitative study of raphe-spinal neurons and serotonergic neurons in 3 medullary raphe nuclei in the cat indicates that more than 80% of the raphe-spinal neurons that project to the spinal cord are serotonergic raphe-spinal neurons in each of the nuclei. More than 85% of the descending raphe-spinal neurons in the two caudal nuclei, nucleus raphe pallidus and nucleus raphe obscurus, are serotonergic, whereas 75% of the raphe-spinal neurons in the more rostrally placed nucleus raphe magnus contain serotonin (5-HT). These results are discussed in relation to descending systems containing both neuropeptides and 5-HT and collateralizing to several spinal segments.

摘要

对猫的3个延髓中缝核的中缝脊髓神经元和5-羟色胺能神经元进行的定量研究表明,投射到脊髓的中缝脊髓神经元中,每个核中超过80%是5-羟色胺能中缝脊髓神经元。在两个尾侧核,即中缝苍白核和中缝隐核中,超过85%的下行中缝脊髓神经元是5-羟色胺能的,而在位置更靠头侧的中缝大核中,75%的中缝脊髓神经元含有5-羟色胺(5-HT)。结合包含神经肽和5-HT并向几个脊髓节段发出侧支的下行系统对这些结果进行了讨论。

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