Hague W E, Maier D B, Schmidt C L, Randolph J F
Obstet Gynecol. 1987 Jun;69(6):926-8.
It has been suggested that tubal ligation may cause luteal phase defects. To assess this possibility, we performed a retrospective analysis of the incidence of luteal phase defects in 72 women who had undergone tubal sterilization. In preparation for tubal reanastomosis, late luteal phase endometrial biopsy was performed. The biopsy was dated in a blind manner and designated either normal or out of phase. This group of patients was compared with a group of 32 women seen for artificial insemination with donor sperm. Luteal phase defect was defined as two biopsies out of phase by two or more days. There were no cases of luteal phase defect in either of the two groups; luteal phase defects were found in 4% of all infertility patients seen during the time of this study. These data do not support the contention that sterilization by tubal ligation leads to an increased incidence of luteal phase defect.
有人提出输卵管结扎可能会导致黄体期缺陷。为了评估这种可能性,我们对72名接受过输卵管绝育术的女性黄体期缺陷的发生率进行了回顾性分析。为准备输卵管再吻合术,在黄体晚期进行了子宫内膜活检。活检结果采用盲法确定日期,并判定为正常或不同期。将这组患者与32名接受供精人工授精的女性进行了比较。黄体期缺陷定义为两次活检结果不同期达两天或更长时间。两组均未出现黄体期缺陷病例;在本研究期间所见的所有不孕患者中,黄体期缺陷的发生率为4%。这些数据并不支持输卵管结扎绝育会导致黄体期缺陷发生率增加的观点。