State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Wuxi Institute for Food Control, Wuxi 214142, China.
Food Chem. 2022 Nov 15;394:133446. doi: 10.1016/j.foodchem.2022.133446. Epub 2022 Jun 9.
Glyphosate, a broad-spectrum and high-efficiency herbicide, could accumulate in the human body through the consumption of agri-food products. Herein, a ratio fluorescence sensor based on rhodamine B-embedded amino-functionalized iron-based metal-organic framework (MOF, NH-MIL-88(Fe)@RhB) bonded with Cu was developed for rapid detection of glyphosate. The synthesized NH-MIL-88(Fe) was a biconical prism and had a cavity for the embedding of RhB as a reference compound. In the presence of Cu, Lewis interactions with NH-MIL-88(Fe)@RhB cause the fluorescence signal to be turned off. When glyphosate was added, the signal was turned on due to chelation with Cu and hydrogen bonding interactions with NH-MIL-88(Fe)@RhB. Under optimal conditions, the developed sensor exhibited a linear range of 0.60-45 μmol L with a response time of less than 1 min. The sensor was applied in the analysis of agri-food products (tea, soybean, wheat, cucumber), with recoveries between 97.93% and 109.06%, indicating its promising application in agri-food safety.
草甘膦是一种广谱、高效的除草剂，可通过食用农产品进入人体。在此，我们开发了一种比率荧光传感器，它基于嵌入氨基功能化铁基金属有机骨架（MOF，NH-MIL-88（Fe）@RhB）的罗丹明 B 键合铜，用于快速检测草甘膦。合成的 NH-MIL-88（Fe）为双锥形棱镜，具有空腔，可嵌入罗丹明 B 作为参考化合物。在存在 Cu 的情况下，与 NH-MIL-88（Fe）@RhB 的路易斯相互作用会导致荧光信号关闭。当添加草甘膦时，由于与 Cu 的螯合以及与 NH-MIL-88（Fe）@RhB 的氢键相互作用，信号会打开。在最佳条件下，开发的传感器在 0.60-45 μmol L 的线性范围内表现出响应时间小于 1 分钟。该传感器应用于农产品（茶、大豆、小麦、黄瓜）的分析，回收率在 97.93%至 109.06%之间，表明其在农产品安全方面具有广阔的应用前景。
