Acibadem Mehmet Ali Aydinlar University, School of Medicine, Istanbul, Turkey.
Acibadem Taksim Hospital, Department of Urology, Istanbul, Turkey.
Immunotherapy. 2022 Jul;14(10):759-764. doi: 10.2217/imt-2021-0203. Epub 2022 Jun 27.
It is unknown whether intravesical bacillus Calmette-Guérin (BCG) is excreted in human breast milk. The US FDA advocates ceasing nursing due to potential adverse reactions. A lactating woman with bladder cancer who elected to receive intravesical immunotherapy with BCG and denied having ceased nursing her newborn is reported. A 42-year-old woman presented with macroscopic hematuria in the 36th week of her pregnancy. Imaging revealed a mass in the bladder. Cystoscopy and resection were performed after childbirth. Pathological examination revealed pT1 urothelial carcinoma. After a thorough discussion of the treatment options, the patient elected intravesical BCG. The infant received intradermal BCG vaccination 2 weeks before the treatment. As a result, the patient could breastfeed without any inadvertent sequela on herself or the baby.
尚不清楚卡介苗（BCG）是否会从人乳中排出。美国食品药品监督管理局（FDA）主张因潜在的不良反应而停止哺乳。报告了一例膀胱癌哺乳期妇女选择接受卡介苗膀胱内免疫治疗并拒绝停止给新生儿哺乳的病例。一名 42 岁女性在怀孕第 36 周时出现肉眼血尿。影像学检查显示膀胱内有肿块。分娩后进行了膀胱镜检查和切除术。病理检查显示 pT1 尿路上皮癌。在充分讨论了治疗方案后，患者选择了膀胱内 BCG。婴儿在治疗前 2 周接受了皮内 BCG 疫苗接种。因此，患者可以进行母乳喂养，而不会对自己或婴儿造成任何意外的后果。
