Hebeler Katherine R, Ogola Gerald, Filardo Giovanni, Mack Michael, Stoler Robert, Mixon Timothy, Szerlip Molly, Edgerton James, Hebeler Robert F
Department of Surgery, Baylor University Medical Center, Dallas, Texas.
Department of Surgery, Baylor Scott & White Research Institute, Dallas, Texas.
Proc (Bayl Univ Med Cent). 2022 May 16;35(4):428-433. doi: 10.1080/08998280.2022.2064581. eCollection 2022.
As more patients undergo transcatheter aortic valve implantation (TAVI), knowledge of 1-year mortality and associated factors becomes increasingly important. After other cardiac procedures, discharge location has been shown to be associated with 1-year mortality. We examined outcomes of TAVI patients discharged home vs an extended care facility (ECF). All TAVI patients from January 1, 2012, to December 31, 2017, were evaluated. Cox proportional hazard regression models with cubic splines were used to estimate the adjusted effect of discharge to ECF on 1-year mortality. A total of 957 (85.6%) patients discharged home were compared to 160 (14.3%) discharged to ECF. On univariate analysis, patients discharged home were younger and had a lower Society of Thoracic Surgeons Predicted Risk of Mortality, higher albumin, and fewer vascular complications and strokes. Patients discharged to ECF had a higher 30-day mortality (3.8% vs. 0.5%, = 0.001) and 1-year mortality (25.7% vs. 8.3%, < 0.001). Cox proportional hazard regression models showed increased risk of 1-year mortality for patients discharged to ECF. In conclusion, patients discharged to ECF had a higher 30-day and 1-year mortality. The strongest predictor of 1-year mortality was discharge to ECF. Society of Thoracic Surgeons Predicted Risk of Mortality score was not a predictor of 1-year mortality.
随着越来越多的患者接受经导管主动脉瓣植入术(TAVI),了解1年死亡率及相关因素变得越发重要。在接受其他心脏手术后,出院地点已被证明与1年死亡率相关。我们研究了出院回家与入住长期护理机构(ECF)的TAVI患者的结局。对2012年1月1日至2017年12月31日期间所有的TAVI患者进行了评估。使用带有三次样条的Cox比例风险回归模型来估计入住ECF对1年死亡率的调整效应。将总共957名(85.6%)出院回家的患者与160名(14.3%)入住ECF的患者进行了比较。单因素分析显示,出院回家的患者更年轻,胸外科医师协会预测的死亡风险更低,白蛋白水平更高,血管并发症和中风更少。入住ECF的患者30天死亡率(3.8%对0.5%,P = 0.001)和1年死亡率(25.7%对8.3%,P < 0.001)更高。Cox比例风险回归模型显示,入住ECF的患者1年死亡风险增加。总之,入住ECF的患者30天和1年死亡率更高。1年死亡率的最强预测因素是入住ECF。胸外科医师协会预测的死亡风险评分不是1年死亡率的预测因素。