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[低氧和高氧条件下照射期间的血脑屏障功能]

[Hematoencephalic barrier function during irradiation under hypo- and hyperoxia].

作者信息

fedorov V P, Ushakov I B

出版信息

Radiobiologiia. 1987 Mar-Apr;27(2):182-8.

PMID:3575663
Abstract

The hematoencephalic barrier status was shown to change depending upon radiation dose and time after exposure. Synergism, additivity, and antagonism were observed after the combined effect of radiation and a changed gas medium. On the whole, hypoxic hypoxia, as opposed to air and oxygen, had a slight radioprotective effect, but after 5 h, no variations were virtually found in the groups animals exposed to superlethal radiation doses in different gas media.

摘要

血脑屏障状态显示会根据辐射剂量和照射后的时间而变化。在辐射与变化的气体介质联合作用后,观察到了协同、相加和拮抗作用。总体而言,与空气和氧气相比,低氧性缺氧具有轻微的辐射防护作用,但在5小时后,实际上在不同气体介质中接受超致死辐射剂量的动物组中未发现差异。

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