准分子激光原位角膜磨镶术后角膜扩张症行角膜胶原交联术的视觉和地形图结果
Visual and Topographic Outcomes of Corneal Collagen Cross Linking for Post LASIK Ectasia.
作者信息
Nasef Mohamed H, El Emam Sharif Y, Haleem Tamer I, Shalaby Wesam S, Allam Waleed A
机构信息
Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Gharbia, Egypt.
出版信息
Clin Ophthalmol. 2022 Jun 20;16:2025-2032. doi: 10.2147/OPTH.S370033. eCollection 2022.
PURPOSE
To assess the topographic and visual outcomes of corneal cross-linking (CXL) for post-LASIK ectasia.
METHODS
A retrospective case series of patients who had progressive post-LASIK ectasia, with at least 2 years of follow-up. They had epithelium-off CXL. Topographical and visual changes were recorded.
RESULTS
The study included 21 eyes of 11 patients. At month 24, the final logMAR corrected distance visual acuity (CDVA) and spherical equivalent (SE) were stable compared to baseline (0.16, and -2.0 diopter (D), respectively). The final Kmean and Kmax were 42.5 and 47.4 D, respectively. Stability or improvement in CDVA, SE, and Kmax was seen in 17 eyes (81%). Significant corneal thinning was seen (438 vs 457 microns, = 0.003). Thinning by 2% or more was seen in 12 eyes (57.1%). Failure of CXL was seen in 4 eyes (19%). No other ocular complications were seen.
CONCLUSION
CXL for post LASIK ectasia is a safe and effective modality. Despite corneal thinning, there was stability or improvement in topographic parameters and CDVA over the 2-year follow-up period.
目的
评估角膜交联术（CXL）治疗准分子激光原位角膜磨镶术（LASIK）后角膜扩张的地形图和视觉效果。
方法
一项回顾性病例系列研究，纳入患有进行性LASIK后角膜扩张且至少随访2年的患者。他们接受了去上皮CXL。记录地形图和视觉变化。
结果
该研究纳入了11例患者的21只眼。在第24个月时，最终的对数最小分辨角矫正远视力（CDVA）和等效球镜度（SE）与基线相比稳定（分别为0.16和-2.0屈光度（D））。最终的平均角膜曲率（Kmean）和最大角膜曲率（Kmax）分别为42.5 D和47.4 D。17只眼（81%）的CDVA、SE和Kmax稳定或改善。观察到明显的角膜变薄（438微米对457微米，P = 0.003）。12只眼（57.1%）角膜变薄2%或更多。4只眼（19%）CXL失败。未观察到其他眼部并发症。
结论
CXL治疗LASIK后角膜扩张是一种安全有效的方法。尽管角膜变薄，但在2年随访期间地形图参数和CDVA保持稳定或改善。
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