Hasan Elisei Moise, Calma Crenguta Livia, Tudor Anca, Vernic Corina, Palade Emanuel, Tudorache Emanuela, Oancea Cristian, Papava Ion
"Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
Department of Functional Sciences, Center of Immuno-Physiology (CIFBIOTEH), "Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
Cancer Manag Res. 2022 Jun 20;14:2041-2052. doi: 10.2147/CMAR.S368992. eCollection 2022.
Depression and anxiety are prevalent issues amongst individuals suffering from thoracic cancer. Gender differences in coping with thoracic cancer have a serious impact upon the management of emotional distress. The purpose of our study has been to assess sex variations in handling anxiety and depression, including the use of coping mechanisms and their relationship with respect to anxiety and depression.
This cross-sectional study registered 18 women and 22 men with non-metastatic lung cancer and operated upon. Pre-operatively and at one month post-operatively, the patients were assessed by means of scales (COPE, GAD-7 and PHQ-9).
Post-operatively, the intensity of depression and anxiety was substantially greater in males than in females (p = 0.049, p = 0.042). Male individuals tended to use coping mechanisms of humour (p = 0.009) and restraint (p = 0.029) significantly more frequently than women. Moreover, in women, depression correlated significantly with denial and behavioural deactivation (rho = 0.465, p = 0.029, respectively, rho = 0.562, p = 0.006); whilst anxiety, similarly, correlated with positive interpretation, behavioural deactivation, and use of social-emotional support (rho = 0.484, p = 0.022, respectively, rho = 0.590, p = 0.004 and rho = 0.502, p = 0.017). Furthermore, in males, depression correlated significantly with mental deactivation, use of social-instrumental and social-emotional support (rho = 0.702, p = 0.001, respectively, rho = 0.505, p=0.033, and rho = 0.773 with p < 0.001), whilst anxiety correlated significantly with mental deactivation, denial, and use of social-emotional support (rho = 0.597, p = 0.009, respectively, rho = 0.553 with p = 0.017 and rho = 0.755, p < 0.001).
There were gender divergences in the use of coping mechanisms and the level of post-surgical anxiety and depression. We found significant positive relationships between some coping mechanisms and depression/anxiety. The patient's gender governs the coping style, which in turn has bearing upon the post-operative evolution.
抑郁和焦虑在胸段癌症患者中普遍存在。应对胸段癌症的性别差异对情绪困扰的管理有严重影响。我们研究的目的是评估应对焦虑和抑郁方面的性别差异，包括应对机制的使用及其与焦虑和抑郁的关系。
这项横断面研究纳入了18名女性和22名男性非转移性肺癌患者并进行了手术。术前及术后1个月，通过量表（COPE、GAD - 7和PHQ - 9）对患者进行评估。
术后，男性的抑郁和焦虑强度显著高于女性（p = 0.049，p = 0.042）。男性使用幽默（p = 0.009）和克制（p = 0.029）应对机制的频率明显高于女性。此外，在女性中，抑郁与否认和行为失活显著相关（rho分别为0.465，p = 0.029；rho为0.562，p = 0.006）；同样，焦虑与积极解释、行为失活以及社会情感支持的使用相关（rho分别为0.484，p = 0.022；rho为0.590，p = 0.004；rho为0.502，p = 0.017）。此外，在男性中，抑郁与心理失活、社会工具性支持和社会情感支持的使用显著相关（rho分别为0.702，p = 0.001；rho为0.505，p = 0.033；rho为0.773，p < 0.001），而焦虑与心理失活、否认以及社会情感支持的使用显著相关（rho分别为0.597，p = 0.009；rho为0.553，p = 0.017；rho为0.755，p < 0.001）。
在应对机制的使用以及术后焦虑和抑郁水平方面存在性别差异。我们发现一些应对机制与抑郁/焦虑之间存在显著的正相关关系。患者的性别决定应对方式，这反过来又影响术后的病情发展。
