Autoimmune Bullous Diseases Research Center, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.
J Cosmet Dermatol. 2022 Nov;21(11):6169-6173. doi: 10.1111/jocd.15183. Epub 2022 Jul 19.
Frontal fibrosing alopecia (FFA) is a primary patterned cicatricial alopecia with different manifestations.
Its incidence is increasing worldwide. Like other types of alopecia, FFA can affect patients' health-related quality of life (HRQOL). However, this effect has been rarely discussed. This study was designed to evaluate HRQOL in patients with FFA.
In this cross-sectional study, 49 patients with confirmed FFA were asked to complete Dermatology Life Quality Index (DLQI) and the 36-Item Short Form Survey (SF-36) questionnaires. Disease severity was evaluated with the Frontal Fibrosing Alopecia Severity Score Index (FFASI).
Significant relation between SF-36 scores and other covariants was not detected. According to the DLQI, most of the patients (54%) had impaired HRQOL, which was of low grade for most of them (84%). Patients with face papules and patients who were in the group of nail, limb, and flexural involvement had significantly lower HRQOL (p-value 0.03).
We found that FFA negatively impacts HRQOL, which was more pronounced in patients with involvement of other ostensible areas.
额部纤维性脱发（FFA）是一种具有不同表现的原发性瘢痕性脱发。
FFA 的发病率在全球范围内呈上升趋势。与其他类型的脱发一样，FFA 会影响患者的健康相关生活质量（HRQOL）。然而，这种影响很少被讨论。本研究旨在评估 FFA 患者的 HRQOL。
在这项横断面研究中，49 例确诊为 FFA 的患者被要求完成皮肤病生活质量指数（DLQI）和 36 项简短健康调查问卷（SF-36）。采用额部纤维性脱发严重程度评分指数（FFASI）评估疾病严重程度。
SF-36 评分与其他协变量之间未发现显著关系。根据 DLQI，大多数患者（54%）的 HRQOL 受损，其中大多数患者（84%）的受损程度较低。面部丘疹患者和指甲、四肢和弯曲部位受累患者的 HRQOL 明显较低（p 值 0.03）。
我们发现 FFA 对 HRQOL 有负面影响，在其他明显受累区域的患者中更为明显。
