Kasymov A R, Rzaev D A, Kalinovsky A V, Voronina E I
Federal Center of Neurosurgery, Novosibirsk, Russia.
Zh Vopr Neirokhir Im N N Burdenko. 2022;86(3):50-55. doi: 10.17116/neiro20228603150.
Olfactory nerve schwannomas are extremely rare. Their origin is still unclear, since olfactory nerve has no Schwann cells. There are about 70 case reports of olfactory nerve schwannoma in the world literature. Original articles devoted to this issue are currently absent.
We present a 55-year-old patient with olfactory nerve schwannoma who underwent surgery at the Federal Center of Neurosurgery in Novosibirsk. MRI revealed extracerebral mass lesion of anterior cranial fossa base with left-sided lateralization resembling meningioma of the olfactory fossa. The patient underwent microsurgical resection of mass lesion of anterior cranial fossa base through left-sided lateral supraorbital craniotomy. The tumor macroscopically resembled schwannoma. Total resection was carried out. Considering morphological structure and immunomorphological characteristics, we verified schwannoma Grade 1.
Olfactory nerve schwannomas are rare tumors with benign histological structure. Relapses after total resection are unlikely. However, further research of this rare pathology and long-term postoperative follow-up are required.
嗅神经鞘瘤极为罕见。其起源仍不明确，因为嗅神经没有施万细胞。世界文献中约有70例嗅神经鞘瘤的病例报告。目前尚无专门针对此问题的原创文章。
我们报告一名55岁患有嗅神经鞘瘤的患者，在新西伯利亚的联邦神经外科中心接受了手术。磁共振成像（MRI）显示颅前窝底部脑外肿块病变，偏向左侧，类似嗅窝脑膜瘤。患者通过左侧眶上开颅术接受了颅前窝底部肿块病变的显微手术切除。肿瘤在宏观上类似神经鞘瘤。进行了全切除。根据形态结构和免疫形态学特征，我们确诊为1级神经鞘瘤。
嗅神经鞘瘤是具有良性组织结构的罕见肿瘤。全切除后复发的可能性不大。然而，需要对这种罕见病理进行进一步研究并进行长期术后随访。
