Department of Neurosurgery.
Department of Outpatient Service, Qilu Hospital of Shandong University (Qingdao), Qingdao, Shandong, China.
J Craniofac Surg. 2024;35(1):e21-e23. doi: 10.1097/SCS.0000000000009705. Epub 2023 Aug 29.
Schwannomas are benign tumors that arise from Schwann cells. Rare cases are shown to arise from the olfactory nerve. The genesis of Olfactory groove schwannoma (OGSs) is still puzzling. Yusda et al hypothesized that olfactory ensheathing cell tumors (OECTs) might be the origin of OGSs.
Here, the authors report the case of a 59-year-old woman who presented with a paroxysmal headache for 1 year. The tumor appeared as hypointensity on T1-weighted images, hyperintensity on T2-weighted, and exhibited strong, heterogeneous enhancement. The tumor was removed through a lateral supraorbital approach. The final pathologic diagnosis was schwannoma. The postoperative period was uneventful after 4 months, and the headache disappeared.
OGSs and OECTs are extremely rare. There are many similarities in clinical manifestations, images, and pathologic findings. OGSs are difficult to distinguish from OECTs.
神经鞘瘤是起源于施万细胞的良性肿瘤。罕见情况下，嗅神经也可发生神经鞘瘤。嗅沟神经鞘瘤（OGS）的起源仍令人费解。Yusda 等人假设嗅鞘细胞肿瘤（OECT）可能是 OGS 的起源。
作者报告了 1 例 59 岁女性患者，其主要表现为阵发性头痛 1 年。肿瘤在 T1 加权像上呈低信号，T2 加权像上呈高信号，增强后呈不均匀强化。通过眶外侧入路切除肿瘤。最终病理诊断为神经鞘瘤。术后 4 个月，患者恢复良好，头痛消失。
OGS 和 OECT 非常罕见。它们在临床表现、影像学和病理表现方面有许多相似之处。OGS 与 OECT 很难区分。
